Presentation is loading. Please wait.

Presentation is loading. Please wait.

Genome-editing Technologies for Gene and Cell Therapy

Published byTeresa Cabrera Rivero Modified over 5 years ago

Similar presentations

Presentation on theme: "Genome-editing Technologies for Gene and Cell Therapy"— Presentation transcript:

1 Genome-editing Technologies for Gene and Cell Therapy
Morgan L Maeder, Charles A Gersbach  Molecular Therapy  Volume 24, Issue 3, Pages (March 2016) DOI: /mt Copyright © 2016 Official journal of the American Society of Gene & Cell Therapy Terms and Conditions

2 Figure 1 Mechanisms of double-strand break repair.
Molecular Therapy  , DOI: ( /mt ) Copyright © 2016 Official journal of the American Society of Gene & Cell Therapy Terms and Conditions

3 Figure 2 Common DNA targeting platforms for genome editing.
Molecular Therapy  , DOI: ( /mt ) Copyright © 2016 Official journal of the American Society of Gene & Cell Therapy Terms and Conditions

4 Figure 3 Ex vivo and in vivo strategies for therapeutic genome editing. Molecular Therapy  , DOI: ( /mt ) Copyright © 2016 Official journal of the American Society of Gene & Cell Therapy Terms and Conditions

5 Figure 4 Diversity of targets for therapeutic genome editing.
Molecular Therapy  , DOI: ( /mt ) Copyright © 2016 Official journal of the American Society of Gene & Cell Therapy Terms and Conditions

Download ppt "Genome-editing Technologies for Gene and Cell Therapy"

Similar presentations

Functional Analysis of the Neurofibromatosis Type 2 Protein by Means of Disease- Causing Point Mutations Renee P. Stokowski, David R. Cox The American.

Functional Analysis of the Neurofibromatosis Type 2 Protein by Means of Disease- Causing Point Mutations Renee P. Stokowski, David R. Cox The American.
Gene Preference in Maple Syrup Urine Disease Mary M. Nellis, Dean J. Danner The American Journal of Human Genetics Volume 68, Issue 1, Pages 232-237 (January.

Gene Preference in Maple Syrup Urine Disease Mary M. Nellis, Dean J. Danner The American Journal of Human Genetics Volume 68, Issue 1, Pages (January.
Ex Vivo Gene Therapy Using Patient iPSC-Derived NSCs Reverses Pathology in the Brain of a Homologous Mouse Model Tagan A. Griffin, Hayley C. Anderson,

Ex Vivo Gene Therapy Using Patient iPSC-Derived NSCs Reverses Pathology in the Brain of a Homologous Mouse Model Tagan A. Griffin, Hayley C. Anderson,
2015 Alzheimer's disease facts and figures Alzheimer's & Dementia: The Journal of the Alzheimer's Association Volume 11, Issue 3, Pages 332-384 (March.

2015 Alzheimer's disease facts and figures Alzheimer's & Dementia: The Journal of the Alzheimer's Association Volume 11, Issue 3, Pages (March.
CyclinD1/CyclinD3 Ratio by Real-Time PCR Improves Specificity for the Diagnosis of Mantle Cell Lymphoma Carol D. Jones, Katherine H. Darnell, Roger A.

CyclinD1/CyclinD3 Ratio by Real-Time PCR Improves Specificity for the Diagnosis of Mantle Cell Lymphoma Carol D. Jones, Katherine H. Darnell, Roger A.
Design and Multiseries Validation of a Web-Based Gene Expression Assay for Predicting Breast Cancer Recurrence and Patient Survival Ryan K. Van Laar The.

Design and Multiseries Validation of a Web-Based Gene Expression Assay for Predicting Breast Cancer Recurrence and Patient Survival Ryan K. Van Laar The.
Volume 20, Issue 2, (February 2012)

Volume 20, Issue 2, (February 2012)
Production and clinical development of nanoparticles for gene delivery

Production and clinical development of nanoparticles for gene delivery
209. Use of Helicobacter pyroli Neutrophil Activating Protein (NAP) as an Immune- Modulatory Agent To Enhance the Efficacy of Oncolytic Adenovirus Therapy.

209. Use of Helicobacter pyroli Neutrophil Activating Protein (NAP) as an Immune- Modulatory Agent To Enhance the Efficacy of Oncolytic Adenovirus Therapy.
Man's Best Friend: Utilizing Naturally Occurring Tumors in Dogs to Improve Chimeric Antigen Receptor T-cell Therapy for Human Cancers  Melinda Mata, Stephen.

Man's Best Friend: Utilizing Naturally Occurring Tumors in Dogs to Improve Chimeric Antigen Receptor T-cell Therapy for Human Cancers  Melinda Mata, Stephen.
627. Non-Invasive, Multimodal Imaging of Microvesicles with Metabolically Biotinylated, Membrane-Bound Gaussia Luciferase    Molecular Therapy  Volume.

627. Non-Invasive, Multimodal Imaging of Microvesicles with Metabolically Biotinylated, Membrane-Bound Gaussia Luciferase    Molecular Therapy  Volume.
Volume 24, Issue 11, Pages (November 2016)

Volume 24, Issue 11, Pages (November 2016)
162. Stability of Polymer/Plasmid DNA Complexes In Vitro and In Vivo

162. Stability of Polymer/Plasmid DNA Complexes In Vitro and In Vivo
281. Rapid Generation of Induced Pluripotent Stem Cells (iPSCs) from the Urine of a Patient with Duchenne Muscular Dystrophy    Molecular Therapy  Volume.

281. Rapid Generation of Induced Pluripotent Stem Cells (iPSCs) from the Urine of a Patient with Duchenne Muscular Dystrophy    Molecular Therapy  Volume.
Direct Conversion of Skin Cells into Blood: Alchemy or Science?

Direct Conversion of Skin Cells into Blood: Alchemy or Science?
Molecular Therapy  Volume 20, Pages S261-S262 (May 2012) DOI: /S (16)

Molecular Therapy  Volume 20, Pages S261-S262 (May 2012) DOI: /S (16)
2016 Curt Stern Award Address: From Rare to Common Diseases: Translating Genetic Discovery to Therapy1  Brendan Lee  The American Journal of Human Genetics 

2016 Curt Stern Award Address: From Rare to Common Diseases: Translating Genetic Discovery to Therapy1  Brendan Lee  The American Journal of Human Genetics 
Evolving Gene Therapy in Primary Immunodeficiency

Evolving Gene Therapy in Primary Immunodeficiency
Gene therapy—where are we?

Gene therapy—where are we?
Volume 20, Issue 6, Pages (June 2012)

Volume 20, Issue 6, Pages (June 2012)

Similar presentations

Ads by Google