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Scott Goldman, MD, Anson Cheung, MD, Joseph E. Bavaria, MD, Michael R

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1 Midterm, multicenter clinical and hemodynamic results for the Trifecta aortic pericardial valve 
Scott Goldman, MD, Anson Cheung, MD, Joseph E. Bavaria, MD, Michael R. Petracek, MD, Mark A. Groh, MD, Hartzell V. Schaff, MD  The Journal of Thoracic and Cardiovascular Surgery  Volume 153, Issue 3, Pages e2 (March 2017) DOI: /j.jtcvs Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

2 Figure 1 Evolution of NYHA functional classification over time. Symbols represent the observed percentages of patients in each NYHA class over time. Solid lines represent the solution for an ordinal logistic longitudinal repeat-measures model with only implant duration as a variable. NYHA, New York Heart Association The Journal of Thoracic and Cardiovascular Surgery  , e2DOI: ( /j.jtcvs ) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

3 Figure 2 A, Evolution of mean transvalvular gradient over time. B, Evolution of EOA over time. C, Evolution of EOAI over time. D, Evolution of AR over time. Symbols represent median values by valve size at each follow-up (A, B, and C), or the percentage of patients in each AR grade (D). Solid lines represent by valve size linear mixed model estimates over time (A, B, and C), or the solution for an ordinal logistic longitudinal repeat-measures model with only implant duration as a variable. EOA, Effective orifice area; EOAI, effective orifice area index; AR, aortic regurgitation. The Journal of Thoracic and Cardiovascular Surgery  , e2DOI: ( /j.jtcvs ) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

4 Figure 3 Kaplan-Meier analysis of freedom from all-cause mortality.
The Journal of Thoracic and Cardiovascular Surgery  , e2DOI: ( /j.jtcvs ) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

5 Figure 4 Kaplan-Meier analysis of freedom from reoperation due to SVD. SVD, Structural valve deterioration. The Journal of Thoracic and Cardiovascular Surgery  , e2DOI: ( /j.jtcvs ) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

6 Figure E1 Premarket to postmarket study flow.
The Journal of Thoracic and Cardiovascular Surgery  , e2DOI: ( /j.jtcvs ) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

7 Freedom from reoperation due to structural valve deterioration was 97
Freedom from reoperation due to structural valve deterioration was 97.3% at 6 years. The Journal of Thoracic and Cardiovascular Surgery  , e2DOI: ( /j.jtcvs ) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

8 Video 1 Surgical implant procedure of a 71-year-old woman who underwent isolated aortic valve replacement with a 21-mm Trifecta valve as part of the premarket approval study with subsequent follow-up in the postapproval study. Echocardiogram performed at 5 years after implant shows no aortic regurgitation, a mean gradient of 9.6 mm Hg, and an effective orifice area index of 0.85 cm2/m2. Video available at: The Journal of Thoracic and Cardiovascular Surgery  , e2DOI: ( /j.jtcvs ) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

9 The Journal of Thoracic and Cardiovascular Surgery 2017 153, 561-569
The Journal of Thoracic and Cardiovascular Surgery  , e2DOI: ( /j.jtcvs ) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

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