Download presentation
Presentation is loading. Please wait.
1
The biodistribution and pharmacokinetics of [68Ga]Ga-1 in the orthotopic xenograft mice using µPET dynamic acquisitions. The biodistribution and pharmacokinetics of [68Ga]Ga-1 in the orthotopic xenograft mice using µPET dynamic acquisitions. (A) Representative images from PET imaging of [68Ga]Ga-1 biodistribution in an orthotopic SOJ6-xenograft mouse 10, 20, 30, 60, 90, and 120 min after i.v. injection (fused PET and contrast-enhanced CT maximum intensity projections images). The orange ovals indicate tumor position. (B) Quantifications in organs from PET imaging of [68Ga]Ga-1 biodistribution in mice 5, 10, 20, 30, 60, 90, and 120 min after i.v. injection. Organ uptakes are represented as mean ± SD percentage injected dose for each organ and each time point (n = 3 mice). Philippe Garrigue et al. PNAS 2018;115:45: ©2018 by National Academy of Sciences
![The biodistribution and pharmacokinetics of [68Ga]Ga-1 in the orthotopic xenograft mice using µPET dynamic acquisitions.](http://slideplayer.com/slide/14771080/90/images/1/The+biodistribution+and+pharmacokinetics+of+%5B68Ga%5DGa-1+in+the+orthotopic+xenograft+mice+using+%C2%B5PET+dynamic+acquisitions..jpg "The biodistribution and pharmacokinetics of [68Ga]Ga-1 in the orthotopic xenograft mice using µPET dynamic acquisitions. (A) Representative images from PET imaging of [68Ga]Ga-1 biodistribution in an orthotopic SOJ6-xenograft mouse 10, 20, 30, 60, 90, and 120 min after i.v. injection (fused PET and contrast-enhanced CT maximum intensity projections images). The orange ovals indicate tumor position. (B) Quantifications in organs from PET imaging of [68Ga]Ga-1 biodistribution in mice 5, 10, 20, 30, 60, 90, and 120 min after i.v. injection. Organ uptakes are represented as mean ± SD percentage injected dose for each organ and each time point (n = 3 mice). Philippe Garrigue et al. PNAS 2018;115:45: ©2018 by National Academy of Sciences.")
Similar presentations
![Supplementary Figure 1. [ 18 F]FHBG is not retained, phosphorylated, or incorporated into the DNA of B16 cells. (A-C) For the in vitro studies a panel.](/21/6248624/big_thumb.jpg "Supplementary Figure 1. [ 18 F]FHBG is not retained, phosphorylated, or incorporated into the DNA of B16 cells. (A-C) For the in vitro studies a panel.>")
![EPR-based tumor uptake of [68Ga]Ga-1 for effective PET imaging.](/90/14771093/big_thumb.jpg "EPR-based tumor uptake of [68Ga]Ga-1 for effective PET imaging.>")
![Quantitative PET Reporter Gene Imaging with [11C]Trimethoprim](/88/16069685/big_thumb.jpg "Quantitative PET Reporter Gene Imaging with [11C]Trimethoprim>")
