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Pioglitazone and risk of bladder cancer in type 2 diabetes mellitus patients: A systematic literature review and meta-analysis of observational studies.

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Presentation on theme: "Pioglitazone and risk of bladder cancer in type 2 diabetes mellitus patients: A systematic literature review and meta-analysis of observational studies."— Presentation transcript:

1 Pioglitazone and risk of bladder cancer in type 2 diabetes mellitus patients: A systematic literature review and meta-analysis of observational studies using real-world data  Mohammad Adil, Rashid Ali Khan, Pinaki Ghosh, Shiva Kumar Venkata, Amit Dattatraya Kandhare, Manju Sharma  Clinical Epidemiology and Global Health  Volume 6, Issue 2, Pages (June 2018) DOI: /j.cegh Copyright © Terms and Conditions

2 Fig. 1 PRISMA flow diagram of study selection process.
Clinical Epidemiology and Global Health 2018 6, 61-68DOI: ( /j.cegh ) Copyright © Terms and Conditions

3 Fig. 2 Forest plot of the association between use of pioglitazone and risk of bladder cancer. Red squares and horizontal lines represent study-specific estimates and 95% CI. The size of the square is proportional to the weights of the individual studies. Black diamond represents pooled estimates (center) and 95% CI (width). Abbreviation: SE: standard error, IV: inverse variance, BC: bladder cancer. Clinical Epidemiology and Global Health 2018 6, 61-68DOI: ( /j.cegh ) Copyright © Terms and Conditions

4 Fig. 3 Forest plot of the association between dose of pioglitazone use and risk of bladder cancer. Red squares and horizontal lines represent study-specific estimates and 95% CI. The size of the square is proportional to the weights of the individual studies. Black diamond represents pooled estimates (center) and 95% CI (width). Abbreviation: SE: standard error, IV: inverse variance, BC: bladder cancer. Clinical Epidemiology and Global Health 2018 6, 61-68DOI: ( /j.cegh ) Copyright © Terms and Conditions

5 Fig. 4 Forest plot of the association between duration of pioglitazone use and risk of bladder cancer. Red squares and horizontal lines represent study-specific estimates and 95% CI. The size of the square is proportional to the weights of the individual studies. Black diamond represents pooled estimates (center) and 95% CI (width). Abbreviation: SE: standard error, IV: inverse variance, BC: bladder cancer. Clinical Epidemiology and Global Health 2018 6, 61-68DOI: ( /j.cegh ) Copyright © Terms and Conditions


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