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Diagnostic performance of [18F]fluorodeoxyglucose positron emission tomography– computed tomography in cyst infection in patients with autosomal dominant.

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Presentation on theme: "Diagnostic performance of [18F]fluorodeoxyglucose positron emission tomography– computed tomography in cyst infection in patients with autosomal dominant."— Presentation transcript:

1 Diagnostic performance of [18F]fluorodeoxyglucose positron emission tomography– computed tomography in cyst infection in patients with autosomal dominant polycystic kidney disease  M. Bobot, C. Ghez, B. Gondouin, M. Sallée, P.E. Fournier, S. Burtey, T. Legris, B. Dussol, Y. Berland, P. Souteyrand, L. Tessonnier, S. Cammilleri, N. Jourde-Chiche  Clinical Microbiology and Infection  Volume 22, Issue 1, Pages (January 2016) DOI: /j.cmi Copyright © 2015 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

2 Fig. 1 Episodes of suspicion of cyst infection among autosomal dominant polycystic kidney disease patients. Black symbols: cyst infection. White symbols: no cyst infection. Clinical Microbiology and Infection  , 71-77DOI: ( /j.cmi ) Copyright © 2015 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

3 Fig. 2 Comparison of imaging techniques in a patient with autosomal dominant polycystic kidney disease and hepatic cyst infection. (a) Low-dose tracking computed tomography (CT) image showing polycystic liver with no spontaneous cyst hyperdensity. (b) [18F]fluorodeoxyglucose (18-FDG) positron emission tomography (PET) image showing hypermetabolism of the hepatic cyst wall. (c) 18-FDG PET–CT fusion image showing hypermetabolism of the cyst wall and allowing precise localization of the infected cyst. (d) CT image with injection of iodinated contrast agent, showing no thickening or enhancement of the cyst wall. (e) T1 magnetic resonance imaging sequence, showing the liquid level within the cyst but no wall thickening. (f) Hepatic cyst puncture with CT, guided by the results of 18-FDG PET–CT, showing positive culture (Escherichia coli). Clinical Microbiology and Infection  , 71-77DOI: ( /j.cmi ) Copyright © 2015 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

4 Fig. 3 [18F]Fluorodeoxyglucose (18-FDG) positron emission tomography–computed tomography (PET–CT) sequence in a patient with hepatic and renal cysts. (a–c) 18-FDG PET–CT image showing pathological hypermetabolism of the left renal cysts (arrowhead) and a hepatic cyst (arrow). (d–f) 18-FDG PET–CT scan performed after 8 weeks of antibiotic treatment (persistence of elevated C-reactive protein level), showing the disappearance of kidney hypermetabolic foci (arrowhead), but the persistence of a hypermetabolic hepatic cyst, which led to the continuation of antibiotics for an additional 2 weeks with complete resolution of blood inflammation. Clinical Microbiology and Infection  , 71-77DOI: ( /j.cmi ) Copyright © 2015 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions


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