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Kay E Gurley, Christopher J Kemp  Current Biology 

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Presentation on theme: "Kay E Gurley, Christopher J Kemp  Current Biology "— Presentation transcript:

1 Synthetic lethality between mutation in Atm and DNA-PKcs during murine embryogenesis 
Kay E Gurley, Christopher J Kemp  Current Biology  Volume 11, Issue 3, Pages (February 2001) DOI: /S (01)

2 Figure 1 Simultaneous loss of DNA-PKcs and Atm results in early embryonic lethality. Shown are embryos within yolk sacs isolated at E8.5. On the left is a Prkdcscid/scid Atm+/+ conceptus showing a normal appearing embryo (arrows) within the yolk sac (A, anterior; P, posterior). The three much smaller concepti on the right are Prkdcscid/scid Atm−/− and show arrested development Current Biology  , DOI: ( /S (01) )


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