1. Figure 2 A stage-based approach to the treatment of NAFLD
Figure 2 | A stage-based approach to the treatment of NAFLD. Lifestyle modifications should be pursued throughout the disease course. Pharmacological therapy is not advised for patients with early-stage NAFLD as a result of their low risk of disease progression; however, in patients with intermediate to late stage NAFLD drugs can be a prescribed based on a risk-benefit analysis. Patients with cirrhosis should be screened for HCC and oesophageal varices. Bariatric surgery can be considered for any patient that meets selection criteria57, and can be safe and effective in carefully selected individuals with advanced fibrosis and cirrhosis, although patients with cirrhosis should only by treated in centres with extensive experience with patients with liver disease. *NASH stage 1–3 fibrosis confirmed by biopsy. HCC, hepatocellular carcinoma.
Rinella, M. E. & Sanyal, A. J. (2016) Management of NAFLD: a stage-based approach
Nat. Rev. Gastroenterol. Hepatol. doi: /nrgastro