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Figure 1 Induction of immune tolerance

Published byHenrique Sintra Lombardi Modified over 5 years ago

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Presentation on theme: "Figure 1 Induction of immune tolerance"— Presentation transcript:

1 Figure 1 Induction of immune tolerance
Figure 1 | Induction of immune tolerance. The mechanisms that control autoreactive B cells and T cells in the periphery include induction of receptor-editing or apoptosis and downregulation of cell activation via inhibitory receptor signalling and modulation of gene expression, as well as cell-extrinsic mechanisms such as limitation of survival factors and growth factors, and suppression by regulatory T (Treg) cells or regulatory B (Breg) cells, or tolerogenic dendritic cells (tolDCs). Pozsgay, J. et al. (2017) Antigen-specific immunotherapies in rheumatic diseases Nat. Rev. Rheumatol. doi: /nrrheum

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