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Figure 7 Treatment algorithm for perianal fistulizing disease
Figure 7 | Treatment algorithm for perianal fistulizing disease. Anatomic characteristics of the fistulas, presence of abscesses and presence of proctitis are the main determinants of the therapeutic strategy. For patients with complex fistulas and/or proctitis, a top-down approach is preferred. Timely assessment of response to medical therapy is essential to initiate alternative therapies or surgery. IMS, immunosuppressant; LIFT, ligation of the intersphincteric fistula tract; MSCs, mesenchymal stem cells. Panés, J. & Rimola, J. (2017) Perianal fistulizing Crohn’s disease: pathogenesis, diagnosis and therapy Nat. Rev. Gastroenterol. Hepatol. doi: /nrgastro
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