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Cortical Sensorimotor Reverberations

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Presentation on theme: "Cortical Sensorimotor Reverberations"— Presentation transcript:

1 Cortical Sensorimotor Reverberations
Sylvain Crochet, Carl C.H. Petersen  Neuron  Volume 86, Issue 5, Pages (June 2015) DOI: /j.neuron Copyright © 2015 Elsevier Inc. Terms and Conditions

2 Figure 1 Reciprocal Excitatory Interactions between Hindlimb Primary Sensorimotor Cortex and Secondary Motor Cortex May Contribute Importantly to Generating Sensory Percepts (A) Schematic drawing of a mouse brain indicating reciprocal excitatory synaptic connectivity between hindlimb primary sensorimotor cortex (S1/M1) and a frontal secondary motor area (M2). S2, secondary somatosensory cortex. (B) Schematic sequence of activity evoked by hindlimb stimulation. Early action potential (AP) firing in S1/M1 (red) is followed by firing of M2 neurons (blue) and then late firing in S1/M1. (C) Schematic drawing of the cortical circuit generating reverberating activity between S1/M1 and M2. Sensory-evoked activity in S1/M1 drives M2 neurons through feedforward connections. M2 drives S1/M1 through feedback connections in part located on the apical dendrites of layer 5 pyramidal cells in layer 1 (L1). Neuron  , DOI: ( /j.neuron ) Copyright © 2015 Elsevier Inc. Terms and Conditions

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