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Nicole C. Bouchard, MD, Mary Ann Howland, PharmD, Howard A

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1 Ischemic Stroke Associated With Use of an Ephedra-Free Dietary Supplement Containing Synephrine 
Nicole C. Bouchard, MD, Mary Ann Howland, PharmD, Howard A. Greller, MD, Robert S. Hoffman, MD, Lewis S. Nelson, MD  Mayo Clinic Proceedings  Volume 80, Issue 4, Pages (April 2005) DOI: / Copyright © 2005 Mayo Foundation for Medical Education and Research Terms and Conditions

2 Figure 1 Chemical structures of synephrine, phenylpropanolamine, amphetamine, and ephedrine. Mayo Clinic Proceedings  , DOI: ( / ) Copyright © 2005 Mayo Foundation for Medical Education and Research Terms and Conditions

3 Figure 2 Non–contrast-enhanced computed tomograms of the head show multiple subacute infarctions (white arrows) in the left cerebellum (left, middle) and left thalamus (right). Mayo Clinic Proceedings  , DOI: ( / ) Copyright © 2005 Mayo Foundation for Medical Education and Research Terms and Conditions

4 Figure 3 Magnetic resonance images of the brain show multiple subacute infarctions (white arrows) in the left cerebellum (left, middle), left thalamus (right, a), and left temporal lobe (right, b). Mayo Clinic Proceedings  , DOI: ( / ) Copyright © 2005 Mayo Foundation for Medical Education and Research Terms and Conditions

5 Figure 4 Generic sympathomimetic phenylethylamine structure with activity alteration. See Table 1 for details. Mayo Clinic Proceedings  , DOI: ( / ) Copyright © 2005 Mayo Foundation for Medical Education and Research Terms and Conditions


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