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Free Radicals in the Context of Ayurvedic Rejuvenative Therapies Presented by Ingrid Naiman for AAPNA on 10 March 2013 AAPNA on 10 March 2013 Copyright.

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Presentation on theme: "Free Radicals in the Context of Ayurvedic Rejuvenative Therapies Presented by Ingrid Naiman for AAPNA on 10 March 2013 AAPNA on 10 March 2013 Copyright."— Presentation transcript:

1 Free Radicals in the Context of Ayurvedic Rejuvenative Therapies Presented by Ingrid Naiman for AAPNA on 10 March 2013 AAPNA on 10 March 2013 Copyright by Dr. Ingrid Naiman 2013

2 2 Kaya Kalpa Curious about Alchemy and Rasayana Herbs Curious about Alchemy and Rasayana Herbs Fukushima Radiation Fukushima Radiation Deep Concern for Humanity Deep Concern for Humanity Many Experiments & Attempts to Apply Theories Many Experiments & Attempts to Apply Theories Copyright by Dr. Ingrid Naiman 2013

3 3 Free Radical Theory One Attempt to Explain the Cause of Aging One Attempt to Explain the Cause of Aging Definition Definition Atom or molecule that has an unpaired electron in the outer orbit Atom or molecule that has an unpaired electron in the outer orbit Problems Problems Causes Oxidative Damage to Tissues Causes Oxidative Damage to Tissues Damages DNA Damages DNA Kills White Blood Cells Kills White Blood Cells Copyright by Dr. Ingrid Naiman 2013

4 4 Free Radicals Associated with Countless Degenerative Diseases Occurs mainly due to damage to lipid membrane Occurs mainly due to damage to lipid membrane Mutagenic Mutagenic Carcinogenic Carcinogenic Cancer, DNA Cancer, DNA Heart Attacks and Strokes, LDL Heart Attacks and Strokes, LDL Everything from wrinkles to Alzheimers disease can be attributed to free radicals. Everything from wrinkles to Alzheimers disease can be attributed to free radicals. Copyright by Dr. Ingrid Naiman 2013

5 5 Causes of Free Radicals Radiation, ionizing as well as electromagnetic fields Radiation, ionizing as well as electromagnetic fields Sunlight & ultraviolet light, especially UV-A Sunlight & ultraviolet light, especially UV-A Pollution Pollution Toxic Metals, Pesticides Toxic Metals, Pesticides Chemicals & Pharmaceuticals Chemicals & Pharmaceuticals Oxidation Oxidation Smoking Smoking Alcohol Alcohol Diet Diet Copyright by Dr. Ingrid Naiman 2013

6 Radiation Damage Copyright by Dr. Ingrid Naiman 2013

7 7 The Vata Connection Vata = Ether + Air Vata = Ether + Air Associated with movement (kinetic energy) Associated with movement (kinetic energy) Leads to change Leads to change Can produce instability Can produce instability Causes sound & sensation Causes sound & sensation Vata dosha is associated with aging Vata dosha is associated with aging Vata destructiveness (wind) can cause: Vata destructiveness (wind) can cause: Corruption of form & structure Corruption of form & structure Cell death resulting in die off debris & ama Cell death resulting in die off debris & ama Copyright by Dr. Ingrid Naiman 2013

8 8 Free Radical Theory Attributed to Denham Harman, 1950s Attributed to Denham Harman, 1950s Lifespan is in inverse proportion to metabolic rate Lifespan is in inverse proportion to metabolic rate The metabolic rate is proportional to oxygen consumption The metabolic rate is proportional to oxygen consumption Oxygen free radicals lead to tissue damage and ultimately death Oxygen free radicals lead to tissue damage and ultimately death Copyright by Dr. Ingrid Naiman 2013

9 9 Oxidation 85% of chronic and degenerative diseases are the results of oxidative damage. 85% of chronic and degenerative diseases are the results of oxidative damage. Yukie Niwa Yukie Niwa Copyright by Dr. Ingrid Naiman 2013

10 10 Stress Increased intake of oxygen usually results in more free radicals Increased intake of oxygen usually results in more free radicals Inflammatory reaction Inflammatory reaction Cortisol Cortisol Ashwagandha lowers cortisol output even when under stress Ashwagandha lowers cortisol output even when under stress Copyright by Dr. Ingrid Naiman 2013

11 11 The Irony Oxygen is necessary to life, but it is a highly toxic, mutagenic gas Oxygen is necessary to life, but it is a highly toxic, mutagenic gas Oxygen is highly reactive and can cause damage by producing reactive oxygen species (ROS) Oxygen is highly reactive and can cause damage by producing reactive oxygen species (ROS) Except for anaerobic species, most living organisms have an inherent capacity to produce antioxidants Except for anaerobic species, most living organisms have an inherent capacity to produce antioxidants Copyright by Dr. Ingrid Naiman 2013

12 12 Types of Free Radicals Superoxide anion: oxygen molecule with extra electron Superoxide anion: oxygen molecule with extra electron Hydroxyl radical Hydroxyl radical highly reactive and damages DNA, carbohydrates, lipids, and proteins highly reactive and damages DNA, carbohydrates, lipids, and proteins Singlet oxygen, catalyst to free radical formation) and damages LDL cholesterol Singlet oxygen, catalyst to free radical formation) and damages LDL cholesterol Copyright by Dr. Ingrid Naiman 2013

13 13 Hydrogen Peroxide Hydrogen peroxide is not a free radical but is involved in the production of ROS Hydrogen peroxide is not a free radical but is involved in the production of ROS ROS which can persist indefinitely ROS which can persist indefinitely Highly mobile Highly mobile Penetrates the cell membrane from outside to damage what is within Penetrates the cell membrane from outside to damage what is within Can form a dangerous hydroxyl free radical or be converted to water and excreted harmlessly Can form a dangerous hydroxyl free radical or be converted to water and excreted harmlessly Copyright by Dr. Ingrid Naiman 2013

14 14 Lipid Peroxidation = Rancidity Affects Mainly Polyunsaturated Fats Affects Mainly Polyunsaturated Fats Processed Foods Processed Foods Meat Meat Cheese Cheese Unsaturated Fats Unsaturated Fats Avocadoes Avocadoes Canola oil, olive oil, peanut oil, sunflower oil Canola oil, olive oil, peanut oil, sunflower oil Macadamia nuts, cashews, almonds, pecans Macadamia nuts, cashews, almonds, pecans Copyright by Dr. Ingrid Naiman 2013

15 Fats in Food Copyright by Dr. Ingrid Naiman 2013

16 16 Herbs to Prevent Rancidity Turmeric, Curcuma longa Turmeric, Curcuma longa Chaparral, Larrea tridentata Chaparral, Larrea tridentata Rosemary Essential Oil Rosemary Essential Oil Copyright by Dr. Ingrid Naiman 2013

17 Hemolysis & Hemorrhage After Fukushima - Electroperforations Copyright by Dr. Ingrid Naiman 2013

18 18 Ghee Significant improvement in lipid structures can be expected when patients switch from vegetable oils to ghee Significant improvement in lipid structures can be expected when patients switch from vegetable oils to ghee Copyright by Dr. Ingrid Naiman 2013

19 19 Clinical Considerations Difference between prevention and cure Difference between prevention and cure Protective Protective Corrective Corrective Examples Examples Chyawan Chyawan Tapaswiji Tapaswiji Copyright by Dr. Ingrid Naiman 2013

20 20 Chyawanprash Ancient herbal jam used to prevent aging and promote longevity, variously attributed to the sage Chywan or the divine Ashwini brothers. Ancient herbal jam used to prevent aging and promote longevity, variously attributed to the sage Chywan or the divine Ashwini brothers. Amalaki fruit Amalaki fruit Herbs & spices Herbs & spices Ghee & sesame oil Ghee & sesame oil Astavarga herbs Astavarga herbs Purified alchemical substances Purified alchemical substances Copyright by Dr. Ingrid Naiman 2013

21 21 Status of the Plasma The plasma is straw-colored and needs to be The plasma is straw-colored and needs to be in the correct pH range in the correct pH range free of chemical & metallic toxins free of chemical & metallic toxins free of fungi, both yeast and mold free of fungi, both yeast and mold free of radioactive particulates and EMF interferences free of radioactive particulates and EMF interferences free of parasites, bacteria, and viruses free of parasites, bacteria, and viruses Copyright by Dr. Ingrid Naiman 2013

22 22 Darkfield Studies Observe live blood Observe live blood Can test almost any diet or protocol to determine the effect on the plasma Can test almost any diet or protocol to determine the effect on the plasma Erythrocytes Erythrocytes White blood cells White blood cells Platelets Platelets Parasites, bacteria, spirochetes, fungi, metallic toxins Parasites, bacteria, spirochetes, fungi, metallic toxins Ama Ama Presence of free radicals can be inferred Presence of free radicals can be inferred Copyright by Dr. Ingrid Naiman 2013

23 Photoshop Enhancement Copyright by Dr. Ingrid Naiman 2013

24 Tourmaline

25 25 Evidence of Free Radicals in Darkfield Copyright by Dr. Ingrid Naiman 2013

26 26 Free Radical Scavenger Sometimes referred to as an antioxidant Sometimes referred to as an antioxidant Renders free radical stable by donating an electron Renders free radical stable by donating an electron May itself become a free radical May itself become a free radical May be removed by white blood cells May be removed by white blood cells May be eliminated from the body May be eliminated from the body Copyright by Dr. Ingrid Naiman 2013

27 27 Antioxidant Electron Donor Electron Donor Stabilizes the Free Radical Stabilizes the Free Radical Renders the Free Radical Harmless Renders the Free Radical Harmless Manages these functions without sustaining damage or becoming itself a free radical Manages these functions without sustaining damage or becoming itself a free radical Copyright by Dr. Ingrid Naiman 2013

28 Electron Donation Copyright by Dr. Ingrid Naiman 2013

29 29 Antioxidant Herbs All Rasayana Herbs All Rasayana Herbs Chyawanprash Chyawanprash Especially high: Triphala Especially high: Triphala Amalaki highest Amalaki highest Haritaki Haritaki Bibhitaki Bibhitaki Arjuna, also radioprotective Arjuna, also radioprotective Highest: Sangre de Grado Highest: Sangre de Grado Copyright by Dr. Ingrid Naiman 2013

30 30 Sangre de Grado Croton lechleri Highest antioxidant rating of 3100 foods, herbs, and supplements tested Highest antioxidant rating of 3100 foods, herbs, and supplements tested mmol/100 grams = 2897.11 mmol/100 grams = 2897.11 4x higher than triphala 4x higher than triphala 90% proanthocyanidins 90% proanthocyanidins Grows in the Rain Forest Grows in the Rain Forest Peru Peru Main use is for bleeding and wound healing Main use is for bleeding and wound healing Causes erythrocyte aggregation Causes erythrocyte aggregation Copyright by Dr. Ingrid Naiman 2013

31 31 Antioxidant Foods, Herbs, & Spices Cloves and Cinnamon Cloves and Cinnamon Fruits & Vegetables Fruits & Vegetables Especially those that are dark in color Especially those that are dark in color Acai and goji berries Acai and goji berries Artichokes and beets Artichokes and beets Dark Chocolate Dark Chocolate Copyright by Dr. Ingrid Naiman 2013

32 32 Myricetin Antioxidant Flavonoid found in berries and grapes Flavonoid found in berries and grapes Walnuts Walnuts Onions Onions Bayberry bark Bayberry bark Red wine Red wine Green tea Green tea Copyright by Dr. Ingrid Naiman 2013

33 33 DNA If the free radical reaction involves strands of the DNA, Serious consequences can result. Copyright by Dr. Ingrid Naiman 2013

34 34 Ayurvedic Herbs for DNA Protection Ashwagandha, Withania somnifera Ashwagandha, Withania somnifera Antioxidant Antioxidant Supports normal cortisol levels Supports normal cortisol levels Protects against lipid peroxidation Protects against lipid peroxidation Bacopa, Bacopa Bacopa, Bacopa monnieri Promotes healthy functioning of neurotransmitters Promotes healthy functioning of neurotransmitters Tulsi, Ocimum tenuiflorum Tulsi, Ocimum tenuiflorum Helps regulate blood sugar and cholesterol Helps regulate blood sugar and cholesterol Copyright by Dr. Ingrid Naiman 2013

35 35 Herbs that Repair DNA Sage (essential oil), Salvia officinalis Sage (essential oil), Salvia officinalis Anti-microbial, antifungal, antioxidant Anti-microbial, antifungal, antioxidant Cats Claw, Uncaria tomentosa Cats Claw, Uncaria tomentosa Improves functioning of DNA & RNA Improves functioning of DNA & RNA Copyright by Dr. Ingrid Naiman 2013

36 36 Neurogenesis Astragalus, Astragalus membranaceus Astragalus, Astragalus membranaceus Extend life of telomeres Extend life of telomeres Improve how immune cells respond to viruses Improve how immune cells respond to viruses Cats Claw, Uncaria tomentosa Cats Claw, Uncaria tomentosa Chromosome repair Chromosome repair Ashwagandha, Withania somnifera Ashwagandha, Withania somnifera Helps regenerate damaged neurons in the brain Helps regenerate damaged neurons in the brain Brain trauma Brain trauma Infection by parasites or spirochetes Infection by parasites or spirochetes Copyright by Dr. Ingrid Naiman 2013

37 37 Rasayanas and Dhatus All rasayanas are antioxidants All rasayanas are antioxidants Promote resistance to disease Promote resistance to disease Promote homeostasis Promote homeostasis Promote health Promote health Promote optimal functioning Promote optimal functioning All rasayanas promote longevity All rasayanas promote longevity Copyright by Dr. Ingrid Naiman 2013

38 38 The Dhatus All nutrients are first assimilated by rasa dhatu and refined for use by rakta dhatu and the other dhatus. All nutrients are first assimilated by rasa dhatu and refined for use by rakta dhatu and the other dhatus. There is assimilation and waste at each stage of tissue renewal. There is assimilation and waste at each stage of tissue renewal. Only what is used as a nutrient forms the dhatu. Only what is used as a nutrient forms the dhatu. Copyright by Dr. Ingrid Naiman 2013

39 39 Rasa Dhatu Plasma Plasma Rasa dhatu is the sea in which blood cells find nourishment. Rasa dhatu is the sea in which blood cells find nourishment. The quality of the fluid, safety of the fluid, and availability of high quality nutrients determines the capacity to sustain, regenerate, and rejuvenate all other tissues of the body. The quality of the fluid, safety of the fluid, and availability of high quality nutrients determines the capacity to sustain, regenerate, and rejuvenate all other tissues of the body. Copyright by Dr. Ingrid Naiman 2013

40 40 Taste of Rasa Dhatu Sweet Sweet Nutritious Nutritious Salty Salty Minerals Minerals Pungent, Sour, Bitter, & Astringent in lesser amounts Pungent, Sour, Bitter, & Astringent in lesser amounts The nutrients needed are best supplied by juice The nutrients needed are best supplied by juice Copyright by Dr. Ingrid Naiman 2013

41 41 Herbs for Rasa Dhatu Guduchi, Tinospora cordifolia Guduchi, Tinospora cordifolia Haritaki, Terminalia chebula Haritaki, Terminalia chebula Shatavari, Asparagus racemosus Shatavari, Asparagus racemosus Jivanti, Leptadenia reticulata Jivanti, Leptadenia reticulata Punarnava, Boerhavia diffusa Punarnava, Boerhavia diffusa Bamboo manna Bamboo manna Shilajit Shilajit Copyright by Dr. Ingrid Naiman 2013

42 42 Western Herbs for Rasa Dhatu Fluids Fluids Water Water Herbal infusions Herbal infusions Juices from fruits or vegetables, especially okra Juices from fruits or vegetables, especially okra Herbs that are mucilaginous and demulcent Herbs that are mucilaginous and demulcent Herbs that are pH balancing Herbs that are pH balancing Herbs that are rich in trace minerals Herbs that are rich in trace minerals Nettles ( Urtica dioica ), sea vegetables, licorice ( Glycyrrhiza glabra), burdock ( Arctium lappa ) Nettles ( Urtica dioica ), sea vegetables, licorice ( Glycyrrhiza glabra), burdock ( Arctium lappa ) Herbs that aid digestion Herbs that aid digestion Lemon Balm ( Melissa officinalis ) Lemon Balm ( Melissa officinalis ) Copyright by Dr. Ingrid Naiman 2013

43 43 Bibliography Balch, James F., The Super Antioxidants, M. Evans & Company, Inc., New York, 1998. Cox, Robert E., The Elixir of Immortality, Inner Traditions, Rochester, VT, 2003. Halliwell, Barry & Gutteridge, John M.C., Free Radicals in Biology and Medicine, Fourth Edition, Oxford University Press, Oxford, 2010. Medicine, Fourth Edition, Oxford University Press, Oxford, 2010. Murthy, T. S. Ananta, Tapaswiji, Sri Vishnu Ashram Trust Publication, Third Edition, Bangalore, 2003. Schechter, Steven R., Fighting Radiation & Chemical Pollutants with Foods, Herbs, & Vitamins, Second Edition, Vitality Ink, Encinitas, CA., 1990. Winston, David & Maimes, Steven, Adaptogens: Herbs for Strength, Stamina, and Stress Relief, Healing Arts Press, Rochster, VT, 2007. Copyright by Dr. Ingrid Naiman 2013

44 44 Bibliography Ayurveda Dash, Bhagwan, Alchemy and Metallic Medicines in Ayurveda, Concept Publishing Company, New Delhi, 1996, Reprinted 2003. Frawley, David, Soma in Yoga and Ayurveda, Lotus Press, Twin Lakes, WI, 2012. Ojha, J.K., Chyawanprash: From Vedic to Genomic Era, Chaukhamba Sanskrit Pratishthan, Delhi, 2003. Sharma, B. D. & Acharya Bal Krishnan, Vitality Strengthening Astavarga Plants, Divya Yog Mandir Trust, Haridwar, 2005 (?) Sharma, Hari, MD, Freedom from Disease, Veda Publishing, Toronto, 1993. Copyright by Dr. Ingrid Naiman 2013

45 45 Internet Sources Benzie, I.F.F. and Wachtel-Galor, S., editors, Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition, Boca Raton (FL): CRC Press, 2011. http://www.ncbi.nlm.nih.gov/books/NBK92763/ Carlsen, Monica H. et al, 2010 http://www.nutritionj.com/content/supplementary/1475-2891-9-3-s1.pdf Copyright by Dr. Ingrid Naiman 2013


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