1. Fig. 1. TP is highly expressed in myeloma.
TP is highly expressed in myeloma. (A) Representative immunohistochemical images of bone marrow (BM) biopsies from tissue arrays from 14 healthy and 14 myeloma patients stained for CD138 and TP. Scale bar, 50 μm. MM, multiple myeloma. (B) Densitometry analysis of CD138+ cells or TP+ cells in (A). Data are box plots showing the distribution and median value of quantitative staining (n = 14). P values were determined by Student’s t test. (C) Western blot analysis of TP expression in normal plasma cells from four healthy donors, malignant plasma cells of six myeloma patients (Pt), and six established human myeloma cell lines. Primary plasma cells were isolated from the BM aspirates of healthy donors or myeloma patients. β-Actin served as loading control. Data are representative of triplicate blots.
Huan Liu et al., Sci Transl Med 2016;8:353ra113
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