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Histopathologic Prognostic Factors in Resected Colorectal Lung Metastases  Satoshi Shiono, MD, Genichiro Ishii, MD, Kanji Nagai, MD, Junji Yoshida, MD,

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Presentation on theme: "Histopathologic Prognostic Factors in Resected Colorectal Lung Metastases  Satoshi Shiono, MD, Genichiro Ishii, MD, Kanji Nagai, MD, Junji Yoshida, MD,"— Presentation transcript:

1 Histopathologic Prognostic Factors in Resected Colorectal Lung Metastases 
Satoshi Shiono, MD, Genichiro Ishii, MD, Kanji Nagai, MD, Junji Yoshida, MD, Mitsuyo Nishimura, MD, Yukinori Murata, MT, Koji Tsuta, MD, Yutaka Nishiwaki, MD, Tetsuro Kodama, MD, Atsushi Ochiai, MD  The Annals of Thoracic Surgery  Volume 79, Issue 1, Pages (January 2005) DOI: /j.athoracsur Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 (A) The criterion for aerogenous spread with floating cancer cell clusters was the presence of tumor clusters floating in the alveolar space (black square) and separated from the main metastatic lesion by at least 0.5 mm (black line) (original magnification, ×50). (B) An enlargement of the tumor clusters within the black square in (A) (original magnification, ×120). The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 Overall survival of the 87 patients after pulmonary metastasectomy. The 5-year survival was 61.4%. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 Survival curves of the patients after pulmonary metastasectomy (A) with and without aerogenous spread with floating cancer cells (ASFC), (B) with and without vascular invasion, (C) with and without lymphatic invasion, and (D) with and without pleural invasion. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

5 Fig 4 Survival curves of patients after pulmonary metastasectomy based on four groups obtained by dividing by the patients according to the presence or absence of aerogenous spread with floating cancer cell clusters (ASFC) and vascular invasion (v). The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

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