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Allogeneic stem cell transplantation after reduced-intensity conditioning in patients with myelofibrosis: a prospective, multicenter study of the Chronic.

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Presentation on theme: "Allogeneic stem cell transplantation after reduced-intensity conditioning in patients with myelofibrosis: a prospective, multicenter study of the Chronic."— Presentation transcript:

1 Allogeneic stem cell transplantation after reduced-intensity conditioning in patients with myelofibrosis: a prospective, multicenter study of the Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation by Nicolaus Kröger, Ernst Holler, Guido Kobbe, Martin Bornhäuser, Rainer Schwerdtfeger, Herrad Baurmann, Arnon Nagler, Wolfgang Bethge, Matthias Stelljes, Lutz Uharek, Hannes Wandt, Andreas Burchert, Paolo Corradini, Jörg Schubert, Martin Kaufmann, Peter Dreger, Gerald G. Wulf, Hermann Einsele, Tatjana Zabelina, Hans Michael Kvasnicka, Jürgen Thiele, Ronald Brand, Axel R. Zander, Dietger Niederwieser, and Theo M. de Witte Blood Volume 114(26): December 17, 2009 ©2009 by American Society of Hematology

2 Survival of patients with myelofibrosis after reduced-intensity allogeneic stem cell transplantation. Survival of patients with myelofibrosis after reduced-intensity allogeneic stem cell transplantation. According to age (A), donor (B), and Lille risk profile (C). Nicolaus Kröger et al. Blood 2009;114: ©2009 by American Society of Hematology

3 Representative fibrosis regression after dose-reduced allograft.
Representative fibrosis regression after dose-reduced allograft. Bone marrow fibrosis grade 3 before transplantation (A), grade 1 after engraftment on day 30 (B), and grade 0 on day 100 after allogeneic stem cell transplantation (C). Image acquisition specifications: Zeiss Axioplan microscope; magnification ×180, oil; Plan Apochromat 20×/0.60 imaging medium/solution; Axiocam HRC camera; Adobe Photoshop software. Nicolaus Kröger et al. Blood 2009;114: ©2009 by American Society of Hematology


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