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Myc Target miRs and Liver Cancer: Small Molecules to Get Myc Sick

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Presentation on theme: "Myc Target miRs and Liver Cancer: Small Molecules to Get Myc Sick"— Presentation transcript:

1 Myc Target miRs and Liver Cancer: Small Molecules to Get Myc Sick
Marie–Annick Buendia, Ludovic Bourre, Stefano Cairo  Gastroenterology  Volume 142, Issue 2, Pages (February 2012) DOI: /j.gastro Copyright © 2012 AGA Institute Terms and Conditions

2 Figure 1 Schematic representation of Myc-mediated oncogenesis in developing and adult liver. The yellow thunderbolts, represent genetic, viral or environmental insults. The impact of Myc activation on liver tumor formation is expressed as a ratio between frequency (f) and latency (l). Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2012 AGA Institute Terms and Conditions

3 Figure 2 Overview of the impact of Myc expression on modulation of miRs that determine hepatic cell fate. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2012 AGA Institute Terms and Conditions


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