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Immunohistochemical (IHC) staining for CD68/CD21 and CD3/CD20 on synovial tissue (ST) of patients with inflammatory bowel disease (IBD) with onset of peripheral.

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Presentation on theme: "Immunohistochemical (IHC) staining for CD68/CD21 and CD3/CD20 on synovial tissue (ST) of patients with inflammatory bowel disease (IBD) with onset of peripheral."— Presentation transcript:

1 Immunohistochemical (IHC) staining for CD68/CD21 and CD3/CD20 on synovial tissue (ST) of patients with inflammatory bowel disease (IBD) with onset of peripheral arthritis under tumour necrosis factor inhibitor (TNF-i), patients with rheumatoid arthritis (RA) naive to treatment and patients with psoriatic arthritis (PsA) naive to treatment. Immunohistochemical (IHC) staining for CD68/CD21 and CD3/CD20 on synovial tissue (ST) of patients with inflammatory bowel disease (IBD) with onset of peripheral arthritis under tumour necrosis factor inhibitor (TNF-i), patients with rheumatoid arthritis (RA) naive to treatment and patients with psoriatic arthritis (PsA) naive to treatment. (A) CD68 (red)/CD21 (brown) staining of ST from patient with IBD with onset of peripheral arthritis under TNF-i treatment. (B) CD68 (red)/CD21 (brown) staining of ST from patient with RA naive to treatment. (C) CD68 (red)/CD21 (brown) staining of ST from patient with PsA naive to treatment (magnification 20× and 40× for the corresponding insert). (D) Lining and sublining IHC score for CD68+ and (E) CD21+ cells in patients with IBD (n=10) with onset of peripheral arthritis under TNF-i, patients with RA naive to treatment (n=15) and patients with PsA naive to treatment (n=12). (F) CD3 (red)/CD20 (brown) staining of ST from patient with IBD with onset of peripheral arthritis under TNF-i treatment. (G) CD3 (red)/CD20 (brown) staining of ST from patient with RA naive to treatment. (H) CD3 (red)/CD20 (brown) staining of ST from patient with PsA naive to treatment (magnification 20× and 40× for the corresponding insert). (I) Lining and sublining IHC score for CD20+ (lining IHC CD20 score in patients with RA naive to treatment vs patients with PsA naive to treatment, *p<0.05; sublining IHC CD20 score in patients with RA naive to treatment vs patients with PsA naive to treatment, *p<0.05) and (J) CD3+ cells in patients with IBD (n=10) with onset of peripheral arthritis under TNF-i, patients with RA naive to treatment (n=15) and patients with PsA naive to treatment (n=10). Stefano Alivernini et al. RMD Open 2018;4:e000667 Copyright © BMJ Publishing Group & EULAR. All rights reserved.

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