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Probiotic supplement reduces risk of necrotizing enterocolitis and mortality in preterm very low-birth-weight infants: an updated meta-analysis of 20.

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Presentation on theme: "Probiotic supplement reduces risk of necrotizing enterocolitis and mortality in preterm very low-birth-weight infants: an updated meta-analysis of 20."— Presentation transcript:

1 Probiotic supplement reduces risk of necrotizing enterocolitis and mortality in preterm very low-birth-weight infants: an updated meta-analysis of 20 randomized, controlled trials  Quanzhen Wang, Jing Dong, Yimin Zhu  Journal of Pediatric Surgery  Volume 47, Issue 1, Pages (January 2012) DOI: /j.jpedsurg Copyright © 2012 Elsevier Inc. Terms and Conditions

2 Fig. 1 Flowchart of selection of studies for inclusion in the meta-analysis. Journal of Pediatric Surgery  , DOI: ( /j.jpedsurg ) Copyright © 2012 Elsevier Inc. Terms and Conditions

3 Fig. 2 Forest plots of probiotics in preterm infants (A, Effect of probiotics on NEC; B, Effect of probiotics on mortality; C, Effect of probiotics on sepsis). Journal of Pediatric Surgery  , DOI: ( /j.jpedsurg ) Copyright © 2012 Elsevier Inc. Terms and Conditions

4 Fig. 3 Funnel plot to assess publication bias (analysis of effect of probiotic supplement on NEC risk including 20 studies; TEgger test = −1.12; 95% CI, −1.82 to 0.56; PEgger test = .278 > .05). Journal of Pediatric Surgery  , DOI: ( /j.jpedsurg ) Copyright © 2012 Elsevier Inc. Terms and Conditions


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