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Arterioscler Thromb Vasc Biol

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1 Arterioscler Thromb Vasc Biol
Persistence of Low HDL-C Levels After Weight Reduction in Older Men With Small LDL Particles by Leslie I. Katzel, Patricia J. Coon, Ellen Rogus, Ronald M. Krauss, and Andrew P. Goldberg Arterioscler Thromb Vasc Biol Volume 15(3): March 1, 1995 Copyright © American Heart Association, Inc. All rights reserved.

2 Plots showing distribution of plasma triglyceride (TG; top) and HDL cholesterol (HDL-C; center) concentrations and LDL peak particle size (bottom) at baseline (○) and after weight loss (□) in men with LDL patterns A and B. Plots showing distribution of plasma triglyceride (TG; top) and HDL cholesterol (HDL-C; center) concentrations and LDL peak particle size (bottom) at baseline (○) and after weight loss (□) in men with LDL patterns A and B. Leslie I. Katzel et al. Arterioscler Thromb Vasc Biol. 1995;15: Copyright © American Heart Association, Inc. All rights reserved.

3 Representative HDL subfraction distributions measured by gradient gel electrophoresis before (PRE) and after (POST) the loss of 12 kg in a subject with LDL pattern A (upper tracing) and a subject with LDL pattern B (lower tracing). Representative HDL subfraction distributions measured by gradient gel electrophoresis before (PRE) and after (POST) the loss of 12 kg in a subject with LDL pattern A (upper tracing) and a subject with LDL pattern B (lower tracing). In the subject with LDL pattern A, an increase in HDL cholesterol (HDL-C) from 0.85 to 1.03 mmol/L was accompanied by a shift in the HDL distribution toward the HDL2b and HDL2a subspecies. In the subject with LDL pattern B, HDL-C rose from 0.67 to only 0.72 mmol/L with no apparent shift in the HDL subclass distribution. Leslie I. Katzel et al. Arterioscler Thromb Vasc Biol. 1995;15: Copyright © American Heart Association, Inc. All rights reserved.


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