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Prefrontal Cortex transcranial Direct Current Stimulation via a Combined High Definition and Conventional Electrode Montage: A FEM modeling study Dennis.

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Presentation on theme: "Prefrontal Cortex transcranial Direct Current Stimulation via a Combined High Definition and Conventional Electrode Montage: A FEM modeling study Dennis."— Presentation transcript:

1 Prefrontal Cortex transcranial Direct Current Stimulation via a Combined High Definition and Conventional Electrode Montage: A FEM modeling study Dennis Q. Truong, Abhishek Datta, Jiansong Xu, Felipe Fregni, and Marom Bikson Neural Engineering Laboratory Department of Biomedical Engineering, City College of the City University of New York, NY *Research supported by The Wallace Coulter Foundation

2 tDCS Basics Typically subthreshold brain stimulation – Action potentials are not directly caused, rather excitability is enhanced or suppressed Enhanced or Suppressed cortical excitability is due to polarity.

3 Heuristic Montages Traditionally montages have been created by rule of thumb – Active Pad over a target region.

4 Heuristic Montages Traditionally montages have been created by rule of thumb – Active Pad over a target region. M1

5 Heuristic Montages Traditionally montages have been created by rule of thumb – Active Pad over a target region. Brocas

6 Heuristic Montages Traditionally montages have been created by rule of thumb – Active Pad over a target region. Wernickes

7 Heuristic Montages Traditionally montages have been created by rule of thumb – Active Pad over a target region. Dorsal Lateral Prefronal Cortex (F8)

8 Heuristic Montages Traditionally montages have been created by rule of thumb – Active Pad over a target region. – Return Pad is simply elsewhere. F8 - SO

9 tDCS is Polarity Sensitive Both the Active and Return stimulate (enhanced or suppressed excitability)

10 An Alternative to Contralateral Supraorbital Both the Active and Return stimulate (enhanced or suppressed excitability) 2x1 Hybrid

11 The Finite Element Model MRI Acquisition Image Segmentation MeshingFEM Solution

12 Heuristic Design is Limited The location of the return pad effects current distribution.

13 Peak Electric field may or may not be on be directly under the active electrodes Stimulation over is not Stimulation of

14 Peak Electric field may or may not be on be directly under the active electrodes Stimulation over is not Stimulation of

15 Summary Montage design does not obey a simple rule of thumb. – Active Electrodes do not necessarily cause peak field at the target. – Return Electrodes need to be carefully considered. Big Picture: Clinicians could use better guidelines for montage designs. i.e. – database of montage models

16 Future Work


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