Presentation on theme: "What do Physicists do in… “REAL LIFE”"— Presentation transcript:
1What do Physicists do in… “REAL LIFE” Many work with doctors in the field ofMedicine
2are essential in the development of many scanning technologies Doctors often need to look inside our bodies without cutting them open…."Medical Physicists"are essential in the development of many scanning technologiesSome you may have heard of…X-rays…..CT scans…..MRI scansAnd new ones you may not have heard of yet….PET scans…..MEG
3Here is your chance to… Find out the basics of how these scans work See how important physics is to modern medicine.
4X-rays Skin X rays Ordinary Light Very little ordinary light can pass through skin. It’s either absorbed at the surface or reflected back…..To “see” inside we need a kind of “light” with more energy…X raysSkin
5Taking “X rays” The patient is placed in front of a source of X RAYS X ray TubeA photo graphic plate is placed on the other side of the patientMost of the X rays pass through the patient’s body…….
6X-rays are absorbed by bone but can pass through skin and soft tissue PhotographicplateboneX rays that are absorbed in the photographic plate cause chemical changes. These show as darkened areas when the plate is developed.Soft tissue
7X-rays are also partly absorbed by some tissues in the body this creates a more subtle picture. PhotographicplateboneSoft tissue
8What part of the body do these X Rays show? A kneeAnswer:
9Advantages of Basic X ray Imaging X rays are easy to produceX ray machines are relatively cheapIn controlled doses X ray images are safe to the patient
10Disadvantages of X ray Imaging In large doses X rays can be harmful to healthImages are only “shadow prints” in one “plane”…..no 3D informationImaging of soft tissues and organs is not always very detailed.
11True or False Challenge… X rays are made of the same “stuff” as visible light. They are both forms of “electromagnetic radiation”.X rays were discovered completely by accident during a physics experiment carried out in 1965.X rays can damage healthy tissues.
12CT Scans another level…. CT or “CAT” scans take X ray imaging to “C” stands for “Computed”“T” stands for “ Tomography”another level….
13In short…. CT scanners are complex X ray machines attached to very clevercomputersusing complicatedmathematics tobuild upimages of our insides.
14The patient is placed on a bed The scanner (X ray machine) is the shape of a ringThe patient is slowly moved through the ring as the scan takes place…
15Looking end on…. X ray tube X Rays are produced in an X ray tube, pass through the patient and are detected by the detectorPatientThe scanner rotates the X ray tube and detector so the patient is scanned from all anglesX ray detector
16The image produced is like a “slice” through the body. There are no photographic plates in CT scanners. All images are created by computers using the information they receive from the x-ray detectorribsspineThe image produced is like a “slice” through the body.
17Advantages of CT scans Images are like “slices” Compared other scanners (MRI and PET) CT machines are quite cheap.
18Disadvantages of CTStill use X rays that can damage healthy tissues (in large doses).Imaging of soft tissues is improved but still not always as detailed as doctors require.
19True or False Challenge… CT stands for Complex Tomography.CT scans make images of your insides in slices. Computers can now take these slices and make a 3D picture of your insides.With CT scans the patient receives a lower dose of x rays than with a standard X ray machine.
20MRI scanners do not use X rays. What do the letters stand for?M……….. MagneticR………… ResonanceI…………. ImagingMRI scanners do not use X rays.
21MRI Explained...Your science studies have shown you that your body is made up of living cells… Which are made up of molecules … Which are made up of atoms
22It’s nucleus contains just one proton The simplest atom is…1 electronHydrogen1 protonIt’s nucleus contains just one proton
23In the 1940’s physicists discovered that the nuclei of some atoms have a property called “SPIN”… ….Like a wobbling spinning top.This causes the nucleus act like a tiny magnet….NS
24After many years of investigation physicists found they could affect the tiny nuclear magnets of hydrogen atoms using very strong magnets and radio waves…Bring in the magnets….This high energy situation cannot be sustained for long. Many will “flip” back….….watch how the magnetic field affects the tiny nuclear magnetsWhen this happens energy is released as a tiny pulse of radio waves !!!SNA pulse of radio waves can cause some of the nuclear magnets absorb energy and “flip”Note: The nuclear magnets can line up in two possible directions
25This tiny pulse of radio waves that can be detected and analysed. The timing, and the energy of these signals, reveals information about the Hydrogen atoms and what types of molecules they are attached to.
26So what has all this got to do with looking inside your body? What is your body mostly made of?What is the chemical name of water?H2OHydrogen in the most abundant element in your body (approx 63% of all the atoms are H)Water
27Organic molecules that make up tissues like FAT MUSCLE TENDONS etc. contain a large number of Hydrogen atoms
28It took physicists over 40 years to turn their discovery of nuclear magnets into images of the human body. But the results are amazing…All this from manipulating the magnetic properties of hydrogen nuclei !
29The patient is placed on a bed and then moved into a large hollow tube. Using an MRI Scanner…The tube contains a very powerful magnet….
30Superconducting Most MRI scanners use magnets but there is a catch…… An electric current passes through a massive coil made of a special “superconducting” materialThis creates a very strong magnet (x times stronger than earths magnetic field)This may seem like a really easy way to create a strong magnetbut there is a catch……
31That’s colder than on the surface of Pluto! Superconducting materials only work correctly when they are really cold…..But not just cold like freezer temperatures….Can you guess how cold?-269That’s colder than on the surface of Pluto!degrees Celsius
32To achieve these temperatures the superconducting coils need to sit in a container filled with… Liquid HeliumThankfully the patient is insulated from this extremely low temperature whilst inside the magnet.
33The magnet used is incredibly strong! Stand 1m away with a large spanner in your hand…. you would not be able to hold on to it.Patients have to remove all metallic objects and credit cards…Patients may have metal objects inside their bodies…
34Patients may be asked the following questions: Have you ever worked in the army or metal working industry?Metal fragments (especially in the eye) could become dislodgedDo you have a pacemaker?If yes you cannot have an MRI scanDo you have any dental implantsSome could become magnetisedDo you have any metal pins or staples in your body?Some could become magnetised and need to be checked that they will hold in place during the scan
35With the patient safety check complete the scan can begin… The part of the body to be scanned is placed in the centre of the primary magnetXThe magnet field produced has to be very steady and strongThis field causes the Hydrogen nuclei in the patients body to line up with the field
36Three further coils are embedded into the tube… Three further coils are embedded into the tube….GRADIENT MAGNETS… these are used to fine tune the magnetic field so particular body parts and tissue types can be focused on.The patient will know when these magnets are switched on…they can make a loud banging noise.XMore coils provide a pulse of radio waves that cause some of the “nuclear magnets” to flip….The machine waits and records any radio signals that are then emitted by the patients body…..
37This information is sent to a computer which uses it to build up an image ….
38CT compared to MRICT scanners scan a patient in “slices” but the angle of the slice depends on how the patient is positioned in the machine.MRI scanners scan a whole section of the body then the doctor can request to view a slice of the patient at any angle…MRI scans can reveal a lot more detail.
40Are MRI Scans Safe?Research has failed to show up any risk to healthPatients do not feel a thing….not even a tingle!Scans typically take 30 mins+Staying still and putting up with clanging noises are the only discomforts a patient has to suffer!a further group of people may find it impossible to have an MRI scan….!BUT
41What is the name of the condition that causes a fear of… confined spaces“Claustrophobia”Many claustrophobics cannot have MRI scans
42True or False Challenge? It is dangerous for a patient to stay in an MRI scanner for too long8. Superconducting magnets are cheap to make and use.9. Claustrophobics are not allowed to have CT scans
43Introductions to PET (positron emission tomography) “snapshot” images are usefulbut doctors sometimes need “real time” pictures of how parts of your body are functioning…e.g. How your heart isfunctioning.Moving images can be achieved with MRI but PET scanning can give excellent results…
44PET SCANNERS LOOK LIKE CT SCANNERS… The key differences:-NO X RAY TUBE.-The ring is surrounded by “Gamma Ray” detectors
45What are “gamma rays” and “positrons” ? A little detour….
46You will have heard of… Antimatter Electrons Protons Neutrons These are the building blocks of atoms.Physicists have discovered a whole host of other particles that exist !!!AND ASWELL: Every particle has it’s own ANTI PARTICLE…Its….equivalentAntimatter
47The antiparticle of the electron is called a… POSITRONWhen an electron and a positron meet they annihilate…The energy released creates 2 gamma rays
48PET scan patients are injected with a specially created substance called a “RADIOTRACER”…. Usually a “Radioactive” typeof glucose.The radiotracer is a source of positrons which leads to the production of gamma rays…INSIDE THE PATIENTS BODY!These pass through the patients body and are picked up by the scanner.
49Looking at the scanner: end on…. The radio tracer produces positrons which annihilate with electrons in the patients body producing pairs of gamma rays.PatientThe energy and position of all the gamma rays are recorded and turned into an image by a computer.Ring of gamma ray detectors
50The radiotracer concentrates itself in certain tissue types… This glucose type radiotracer has concentrated itself in high glucose using cells like the brain, kidneys and cancer cells.
51PET Scans are very expensive… The biggest cost is in the production of the RADIOTRACERS.The hospital needs to have access to a “CYCLOTRON” to create them (several million euro to buy one!)Radiotracers have to be used straight after they are produced….they cannot be stored.
52True or False?10. PET scanning poses no risk to patient health. Doctors can use them as often as they like.11. “Antimatter” is just an idea invented by science fiction writers.12. Gamma rays are also a form of “electromagnetic radiation” like light and X rays.
53Brief Introduction to MEG (magnetoencephalography) MEG is different to all the other techniques…It doesn’t put anything into a patients body….No X rays/Strong Magnetic Fields/Radio waves/Radiotracers.It just measures something that is already there…
54Your body is full of tiny electric currents! These tiny currents produce tiny magnetic fieldsMEG is able to measure some of these.
55MEG is mostly used to image brain activity. MEG scanners measure tiny magnetic fields produced by electrical brain activity.These fields are so weak (10,000 million times weaker that the earths magnetic field) that the scanner needs to be in a specially shielded room.
56So now you know how important PHYSICS is to MEDICINE MRICTMEGX raysPET