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A. Marc Gillinov, MD, Tomislav Mihaljevic, MD, Eugene H

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1 Should Patients With Severe Degenerative Mitral Regurgitation Delay Surgery Until Symptoms Develop? 
A. Marc Gillinov, MD, Tomislav Mihaljevic, MD, Eugene H. Blackstone, MD, Kristopher George, MD, Lars G. Svensson, MD, Edward R. Nowicki, MD, MS, Joseph F. Sabik, MD, Penny L. Houghtaling, MS, Brian Griffin, MD  The Annals of Thoracic Surgery  Volume 90, Issue 2, Pages (August 2010) DOI: /j.athoracsur Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Temporal trend in New York Heart Association (NYHA) functional class among patients undergoing mitral valve surgery. (Solid circles = class I; open circles = class II; squares = class III; diamonds = class IV.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 Hospital mortality according to preoperative New York Heart Association (NYHA) functional class. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 Survival according to New York Heart Association (NYHA) functional class. (A) Unadjusted survival. (Solid circles = class I; open circles = class II; triangles = class III; squares = class IV.) (B) Survival in propensity-matched groups. (Solid circles = class I; open circles = class II; triangles = class III/IV.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

5 Fig 4 Mitral regurgitation grades over time. (Squares = grade 0; Open circles = grade 1; solid circles = grade 2; triangles = grade 3/4.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions


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