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Aspirin and Clopidogrel Resistance

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Presentation on theme: "Aspirin and Clopidogrel Resistance"— Presentation transcript:

1 Aspirin and Clopidogrel Resistance
Erin D. Michos, MD, Reza Ardehali, MD, PhD, Roger S. Blumenthal, MD, Richard A. Lange, MD, Hossein Ardehali, MD, PhD  Mayo Clinic Proceedings  Volume 81, Issue 4, Pages (April 2006) DOI: / Copyright © 2006 Mayo Foundation for Medical Education and Research Terms and Conditions

2 Figure 1 Sites of action of aspirin and clopidogrel. ADP = adenosine diphosphate; COX-1 = cyclooxygenase 1; GP = glycoprotein; TXA2 = thromboxane A2. Mayo Clinic Proceedings  , DOI: ( / ) Copyright © 2006 Mayo Foundation for Medical Education and Research Terms and Conditions

3 Figure 2 Proposed mechanisms for aspirin resistance. ASA = aspirin; COX = cyclooxygenase; NSAIDs = nonsteroidal anti-inflammatory drugs; TXA2 = thromboxane A2. Mayo Clinic Proceedings  , DOI: ( / ) Copyright © 2006 Mayo Foundation for Medical Education and Research Terms and Conditions

4 Figure 3 Proposed mechanisms for clopidogrel resistance. ACS = acute coronary syndrome. Mayo Clinic Proceedings  , DOI: ( / ) Copyright © 2006 Mayo Foundation for Medical Education and Research Terms and Conditions


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