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Migraine Patient Survey

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1 Migraine Patient Survey
Provided By:

2 About This Research

3 Objective The overall objective of this research is to explore the unmet migraine treatment needs of migraine sufferers. Additional objectives of this research are to: Understand patient perceptions and attitudes toward current treatment methods Determine key attributes associated with effective treatments Identify expectations of treatment and where current treatments are falling short 3

4 Research Methodology National custom telephone survey
Among medically diagnosed migraine patients years of age Total n = 500 with an overall margin of error of ± 4.5%, in 95 out of 100 cases. Computer-assisted telephone interviewing. Data collected March 19- March 27, 2010 Who How Many How When What 4

5 Key Takeaways

6 Executive Summary Sufferers lack a standardized, effective treatment option for combating serious symptoms and side effects of migraines. The most common type of migraine attack, that affects 69% of sufferers, is the rapid onset migraine (it just sneaks up on you) with or without nausea and vomiting. And, over half (53%) of sufferers experience a migraine on a monthly basis. And yet, three- fourths of sufferers (74%) admit they do not record their migraine attacks. When it comes to treatment options, over-the-counter medications (72%), lifestyle management (72%), and prescription migraine treatments (57%) top sufferers most common lines of defense. Only half of migraine sufferers agree, when I get a migraine with nausea or vomiting, after taking my migraine medication, I typically get fast relief that allows me to get back to my work/life. And only 38% of sufferers strongly agree I am satisfied with how quickly my current medication works. 6

7 Executive Summary Sufferers are talking to their doctors about the best treatment options available for their migraine episodes. Over half of oral medication users (55%) talk to their doctor about their migraine attacks once every 6-12 months. Most often sufferers admit they discuss ways to manage my migraine attacks (79%) and possible lifestyle changes (79%). In these conversations, 62% of oral medication users said they mentioned that prescription oral tablets don’t always work for all their migraine attacks. Users of oral prescriptions want an effective option to take during a migraine to help combat their serious symptoms. Over half (54%) of migraine sufferers use oral prescription medications to manage their migraines. Of those not taking prescriptions, cost (18%) and experienced side effects (14%) are the main reasons why many sufferers are not taking prescription medication to manage their migraines. Among oral medication users, half (54%) admit they have experienced migraine attacks where they didn’t think prescription oral tablets would be an effective treatment option. When prescription oral tablets aren’t an effective treatment option, one-quarter (23%) of sufferers admit they just have to wait it out and endure the headache. 7

8 Executive Summary While sufferers are satisfied with their current treatment options, there is an opportunity to better meet sufferers overall needs. The majority of prescription medication users (87%) are satisfied with their current prescription medication. And yet, 31% of sufferers admit their doctor has prescribed more than one medication at a time to manage their migraines. Prescription medication users look to migraine medications to offer the quickest relief possible regardless of the form (41%), the ability to use the medication and continue with regular activities (38%), and for the medication to be lower in cost and covered by insurance (38%). 8

9 Detailed Findings

10 Migraines: Managing The Pain

11 Frequency of Migraines
Over half of migraine sufferers admit to having a migraine at least once a month. How often do you suffer from migraines? 52% suffer at least once per month Q1. How often do you suffer from migraines? Would you say…? 11

12 Type of Migraine Rapid onset migraines and migraines with nausea and/or vomiting occur most often among sufferers. Other migraine occurrence Migraine upon waking in the morning 49% 26% Rapid onset migraine Migraine with nausea and/or vomiting 69% 66% Q2. Do your migraines occur in any or all of the following ways? 12

13 Migraine Symptoms And, over four in ten sufferers, report rapid onset migraines occur most frequently. Which do experience most frequently? Q3. Of these migraine attacks, which do you experience most frequently? 13

14 Tracking Your Migraines
And yet, only the minority of sufferers track their migraine attacks. Q4. If you record your migraine attacks, what tools do you use? 14

15 Treatment Options Available
Sufferers are aware of a wide variety of treatment options including prescription pills, OTC medications, and lifestyle management changes. Q5. Which of the following migraine treatment options are you aware of? XX% reported none of the above 15

16 Options For Treatment And yet, the majority of sufferers admit they turn to over-the-counter medications to treat their migraine attacks. N=500 Total % I take over-the-counter medications to treat my migraine attacks 62 I take prescription medication when I feel a migraine coming on or begin experiencing migraine attacks 42 I take prescription medication, but wait to use it until I am sure it is really a migraine 36 I have stopped taking prescription/OTC medication to treat my migraine attacks 21 I take a daily prescription medication to prevent migraine attacks 16 I have never taken prescription medication to treat my migraine attacks 4 16 Q6. Which, if any, of the following best describes your current migraine treatment options?

17 Current Treatments Being Used
Regularly sufferers try over-the-counter medications, lifestyle management, and prescription oral pills or tablets to manage their migraines. As suffers age, they are more likely to use lifestyle management as a way to manage their migraines; ages (56%), ages (72%), ages (76%), and ages (73%). N=500 Total % Over-the-counter medications 72 Lifestyle management (e.g. diet, sleep, exercise, stress reduction) Prescription oral pills or tablets 54 Alternative remedies including acupuncture, herbs, and chiropractic/osteopathic manipulation 30 Prescription injection 8 Prescription nasal spray 7 Prescription needle-free injection 3 Something else 5 2% reported none of the above 17 Q7. Which, if any, of the following best describes the current treatment options you use to manage your migraine?

18 Prescription Medications
Of those taking prescription medications, Imitrex tablets are most often prescribed. 69% of Sufferers take Oral Meds 56% admit to taking other forms (nasal sprays, injections, etc…) of Rx meds Users of Rx Meds Total % N=284 Imitrex Tablets 42 AXERT 4 Maxalt 18 Amerge Imitrex STATdose 13 Zomig Nasal Spray 3 Treximet 12 Ergotamines Relpax 11 Frova 2 Imitrex nasal spray 10 SUMAVEL 1 Zomig Tablets 9 Something else 40 6% reported none of the above 18 Q8. Which if any of the following prescription medications do you take for migraines?

19 Other Medications for Migraines
Other medications migraine sufferers are taking include: Topamax, butalbital/acetaminophen, and prescription and regular strength over-the-counter medications. Word Cloud of Other responses Q9. If you are not taking prescription medications to manage your migraine, please explain why? (Other Coded Responses) 19

20 Barriers To Prescription Medications
Barriers to prescription medications most often include cost and side effects. Why do you not use prescription medications to manage your migraine attacks? Midwesterners are significantly more concerned with cost than in other areas; Midwest (26%), Northeast (5%), South (19%), and West (10%). N= Those not taking a prescription medication Q9. If you are not taking prescription medications to manage your migraine, please explain why? 20

21 Barriers To Prescription Medications
And often times OTC medications works well enough or sufferers just don’t see a need for taking prescription medications. Word Cloud of Other responses Q9. If you are not taking prescription medications to manage your migraine, please explain why? (Other Coded Responses) 21

22 Satisfaction With Current Treatment Options

23 Satisfaction with Current Medication
Nearly nine in ten sufferers admit they are satisfied with their current prescription medications. 87% Very or Somewhat Satisfied Oral prescription medication users are more satisfied with their current medication than users of other prescription medications (89% vs. 62%). N= 284 Those who use prescription medication Q10. Overall, how satisfied are you with your current prescription medication(s)? Are you…? 23

24 Satisfaction with Speed of Treatment
While three-fourths of suffers admit they are satisfied with how quickly their medication works, suffers are less satisfied with how quickly they can be back to work/life after taking migraine medications for migraines upon waking . % Agree Q10. Overall, how satisfied are you with your current prescription medication(s)? Are you…? 24

25 Important Attributes in a Medication
When it comes to relief, those who take prescription oral medications want a medication that is inexpensive/covered by insurance and offers quick relief, while not disrupting their day. N= 271 Those who take a n oral prescription medication Most Important The quickest relief possible regardless of form (i.e. pill, nasal, injection, etc…) 41 Able to use medication and continue with regular activities 38 Lower cost, covered by insurance Is effective at any stage of the migraine 32 Easy to use 29 Few side effects 24 I can use it effectively even when nauseated or vomiting 19 Long-lasting effect 17 No needle required to administer 16 Other 3 2% reported none of the above/not sure Q11. What is the most important attribute of a prescription migraine medication? 25

26 Current Attributes in Treatment Options
And yet, nearly half of prescription users don’t feel their medication provides the quickest relief possible at a low cost. N= 271 Those who take a n oral prescription medication Current Attributes Easy to use 85 No needle required to administer 67 Few side effects 65 Able to use medication and continue with regular activities The quickest relief possible regardless of form (i.e. pill, nasal, injection, etc…) 56 Lower cost, covered by insurance Long-lasting effect I can use it effectively even when nauseated or vomiting Is effective at any stage of the migraine 53 Other 2 3% reported none of the above/not sure Q Does your current treatment offer the following attributes? 26

27 Satisfaction With Imitrex STATdose
Overall, sufferers who are prescribed Imitrex STATdose are satisfied with the way the treatment relives their pain. 84% Very or Somewhat Satisfied N= 32 Those who use STATdose *Caution Small Base Size Q13. if you have ever been prescribed Imitrex STATdose (sumatriptan injection) to manage your migraine, how satisfied were you with how well it relieved your migraine? 27

28 Satisfaction With Ease of Use
And sufferers are satisfied with how easy it is to use STATdose. 91% Very or Somewhat Satisfied N= 32 Those who use STATdose *Caution Small Base Size Q14. How satisfied were you with how easy it was to use Imitrex STATdose (sumatriptan injection)? 28

29 Reasons for Not Trying STATdose
The majority of those not taking STATdose are not opposed to the medication or its side effects, but rather were unaware of this type of medication or the doctor recommend another treatment. 2% reported not sure N= 355 Those not taking STATdose Q15. Which of the following statements best describes why you have not used Imitrex STATdose (sumatriptan injection)? 29

30 The Truth About Oral Medications

31 The Need For Alternative Options
Pills aren’t always an effective treatment option for the majority of migraine sufferers. Yes 54% No 44% N= 271 Those who take an oral prescription medication Q20. If you use oral prescription migraine medications, have you ever experienced migraine attacks where you didn’t think prescription oral tablets would be an effective treatment option? 31

32 Managing Migraines And less than two in ten sufferers feel they have other prescribed medications when oral pills are not an option. When oral pills are not an option, how do you mange your migraine attacks? N= 271 Those who take prescription oral medication Q21. When prescription oral tablets aren’t an effective treatment option given the nature of your migraine attack, how do you manage your migraine? 32

33 Sickness from Medications…
Nausea and vomiting prohibits one-third of sufferers from taking their prescription medications. Yes 37% No 63% N= 271 Those who take prescription oral medication Q22. Have you ever delayed or avoided taking your medication due to nausea or vomiting resulting from the migraine? 33

34 Getting Back to Life… Nearly half of sufferers admit, they don’t get fast relief after taking their medication to relieve a migraine with nausea or vomiting. 46% Disagree When I get a migraine with nausea or vomiting, after taking my migraine medication, I typically get fast relief that allows me to get back to my work/lifestyle 54% Agree N= 500 Q19. Please tell me how much you agree or disagree with each of the following 34

35 Discussing with Your Doctor…
And two-thirds of sufferers admit they are talking to their doctors about this problem. Yes 62% No 36% N= 271 Those who take prescription oral medication Q24. have you mentioned to your doctor that prescription oral tablets don’t always work for all your migraine attacks, such as those that include nauseas or vomiting? 35

36 Talking With Your Doctor

37 Working With Your Doctor to Relieve Symptoms
The majority of sufferers discuss lifestyle changes and ways to manage their migraine attacks with their doctors. 79% Agree My doctor and I discuss lifestyle changes that could help prevent migraines from occurring 79% Agree My doctor and I discuss ways to manage my migraine attacks N=500 Q19. Please tell me how much you agree or disagree with each of the following? 37

38 Seeking Migraine Knowledge
And, over half of sufferers are talking to their doctor twice a year or more about their migraine attacks. 1% reported not sure N= 271 Those who take prescription oral medication Q23. How often, if ever, do you talk to your doctor about your migraine attacks? 38

39 One Problem, Multiple Medications…
Less than three in ten sufferers agree my doctor told me I need more than one medication or treatment option to effectively manage my varying migraine occurrences. 26% Agree My doctor told me that I need more than one medication or treatment option to effectively manage my varying migraine occurrences. N=500 Q19. Please tell me how much you agree or disagree with each of the following? 39 25.

40 One Problem, Multiple Medications…
Yet, nearly one-third of patients have been prescribed multiple medications for their migraine symptoms. Yes 31% No 69% N=500 Q16. Has your doctor ever prescribed more than one medication at a time (e.g. oral tablet and injection or nasal spray, etc…) to mange your migraine? 40

41 Reasons for Multiple Medications
Nearly one-third of sufferers admit I take one kind of medicine daily and a different one at the time of a migraine attack. 16% reported not sure N= 154 Those taking more than one medication Q17. What was the primary reason for the doctor prescribing more than one medication at a time? 41

42 Seeking Migraine Knowledge
Most often multiple medications are requested because the medicine didn’t relieve the migraine symptoms. 25% Didn’t relieve my migraine 17% Didn’t work for certain migraine attacks Didn’t work fast enough Caused side effects 8% 9% Change/update colors 37% Didn’t ask the doctor for an alternative treatment N= 271 Those who take an oral prescription medication Q25. Which of the following is – or would be- the primary reason for asking your doctor about prescribing an alternative or additional treatment to oral tablets? 42

43 Word Cloud of Other responses
Improving Treatment When it comes to improving the current treatment methods, sufferers want medication that works better, and overall is more affordable. Word Cloud of Other responses Q18. In your opinion, what if anything, can be done to improve your current treatment? 43

44 APPENDIX A: DEMOGRAPHICS

45 Demographics Gender Female: 88% Male: 12% Income Under $25K: 12%
$25K to 49,999: 22% $50K to 74,999: 24% $75K to 99,999: 16% 100K or more: 15% Age 18-24: 0% 25-30: 8% 31-35: 33% 36-40: 27% 41-45: 32% 45+: 0% Employment Employed: 69% Unemployed: 31% Region Midwest: 39% South: 33% Northeast: 17% West: 10% Race/Ethnicity White: 92% Black: 2% Hispanic: 2% Other: % 45

46 Attitudinal Statements
Total % N=500 Agree (Strongly + Somewhat) Strongly Agree Somewhat Agree My doctor and I discuss lifestyle changes that could help prevent migraines from occurring 79 56 22 My doctor and I discuss ways to manage my migraine attacks 54 25 I am satisfied with how quickly my migraine medication works 74 38 36 When my migraine comes on suddenly, after taking my migraine medication I typically get fast relief that allows me to get back to my work/life 64 39 When I awaken in the morning with a migraine, after taking my migraine medication I typically get fast relief that allows me to get back to my work/life 59 26 33 When I get a migraine with nausea or vomiting, after taking my migraine medication, I typically get fast relief that allows me to get back to my work/life 19 35 My doctor told me that I need more than one medication or treatment option to effectively manage my varying migraine occurrences (e.g. upon waking in the morning, with nausea/vomiting, rapid onset, etc…) 13 Make as header statements/start of sections 46 Q19. Please tell me how much you agree or disagree with each of the following?


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