Presentation is loading. Please wait.

Presentation is loading. Please wait.

Figure 1. Melatonin levels in CSF of control subjects (n = 82) and AD patients (n = 85). *, P< 0.0001. Decreased Melatonin Levels in Postmortem Cerebrospinal.

Published byLaurel Clarke Modified over 6 years ago

Similar presentations

Presentation on theme: "Figure 1. Melatonin levels in CSF of control subjects (n = 82) and AD patients (n = 85). *, P< 0.0001. Decreased Melatonin Levels in Postmortem Cerebrospinal."— Presentation transcript:

1 Figure 1. Melatonin levels in CSF of control subjects (n = 82) and AD patients (n = 85). *, P< Decreased Melatonin Levels in Postmortem Cerebrospinal Fluid in Relation to Aging, Alzheimer’s Disease, and Apolipoprotein E-ε4/4 Genotype1 J Clin Endocrinol Metab. 1999;84(1): doi: /jcem J Clin Endocrinol Metab | Copyright © 1999 by The Endocrine Society

2 Figure 2. Melatonin levels in CSF of control subjects, 41–80 yr of age (n = 53) and older than 80 yr (n = 29). *, P < 0.01. Decreased Melatonin Levels in Postmortem Cerebrospinal Fluid in Relation to Aging, Alzheimer’s Disease, and Apolipoprotein E-ε4/4 Genotype1 J Clin Endocrinol Metab. 1999;84(1): doi: /jcem J Clin Endocrinol Metab | Copyright © 1999 by The Endocrine Society

3 Figure 3. Melatonin levels in CSF of control subjects and AD in relation to the clock time of death. Note that the overall levels of melatonin in AD were significantly lower than those in controls and that there was no obvious day/night rhythm in CSF melatonin levels in either controls or AD patients. Decreased Melatonin Levels in Postmortem Cerebrospinal Fluid in Relation to Aging, Alzheimer’s Disease, and Apolipoprotein E-ε4/4 Genotype1 J Clin Endocrinol Metab. 1999;84(1): doi: /jcem J Clin Endocrinol Metab | Copyright © 1999 by The Endocrine Society

4 Figure 4. Melatonin levels in CSF in control subjects and AD in relation to the month of death. Note that there was no significant seasonal rhythm in CSF melatonin levels in either controls or AD patients. Decreased Melatonin Levels in Postmortem Cerebrospinal Fluid in Relation to Aging, Alzheimer’s Disease, and Apolipoprotein E-ε4/4 Genotype1 J Clin Endocrinol Metab. 1999;84(1): doi: /jcem J Clin Endocrinol Metab | Copyright © 1999 by The Endocrine Society

5 Figure 5. Melatonin levels in CSF of AD patients who expressed ApoE-∈3/4 (n = 32) and ApoE-∈4/4 (n = 17). *, P < 0.02. Decreased Melatonin Levels in Postmortem Cerebrospinal Fluid in Relation to Aging, Alzheimer’s Disease, and Apolipoprotein E-ε4/4 Genotype1 J Clin Endocrinol Metab. 1999;84(1): doi: /jcem J Clin Endocrinol Metab | Copyright © 1999 by The Endocrine Society

Download ppt "Figure 1. Melatonin levels in CSF of control subjects (n = 82) and AD patients (n = 85). *, P< 0.0001. Decreased Melatonin Levels in Postmortem Cerebrospinal."

Similar presentations

SORVEGLIANZA DELLE MALATTIE NEOPLASTICHE. Cancer statistics, 2013 CA: A Cancer Journal for Clinicians Volume 63, Issue 1, pages 11-30, 17 JAN 2013 DOI:

SORVEGLIANZA DELLE MALATTIE NEOPLASTICHE. Cancer statistics, 2013 CA: A Cancer Journal for Clinicians Volume 63, Issue 1, pages 11-30, 17 JAN 2013 DOI:
Date of download: 9/17/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Reduction of SorLA/LR11, a Sorting Protein Limiting.

Date of download: 9/17/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Reduction of SorLA/LR11, a Sorting Protein Limiting.
Figure 1. Mass of rapid insulin secretory bursts and ApEn values in young and old subjects. Increased Disorderliness of Basal Insulin Release, Attenuated.

Figure 1. Mass of rapid insulin secretory bursts and ApEn values in young and old subjects. Increased Disorderliness of Basal Insulin Release, Attenuated.
Figure 2. ROC curves for fasting values (A) and OGTT values (B) for detecting insulin resistance in PCOS women. Sensitivity is plotted against 1 − specificity.

Figure 2. ROC curves for fasting values (A) and OGTT values (B) for detecting insulin resistance in PCOS women. Sensitivity is plotted against 1 − specificity.
Figure 2. Summary of trial events

Figure 2. Summary of trial events
(Adapted, with permission, from Fagin JA

(Adapted, with permission, from Fagin JA
Figure 1. Twenty-four-hour plasma ACTH concentrations in insomniacs (▪) and controls (○). The thick black line indicates the sleep recording period. The.

Figure 1. Twenty-four-hour plasma ACTH concentrations in insomniacs (▪) and controls (○). The thick black line indicates the sleep recording period. The.
Fig. 1. Baseline and 3-month infusion protocol

Fig. 1. Baseline and 3-month infusion protocol
Circadian Rhythms of Women with Fibromyalgia1

Circadian Rhythms of Women with Fibromyalgia1
Figure 1. Schematic representation of TSHR

Figure 1. Schematic representation of TSHR
Fig. 1. Time line for investigations

Fig. 1. Time line for investigations
Fig. 1. Kaplan-Meir survival curves for Stoke Cushing's patients, with follow-up duration in years on the x-axis. Number of patients in each subgroup is.

Fig. 1. Kaplan-Meir survival curves for Stoke Cushing's patients, with follow-up duration in years on the x-axis. Number of patients in each subgroup is.
Numbers correspond to section of text addressing selected clinical issue. From: Treatment of Symptoms of the Menopause: An Endocrine Society Clinical Practice.

Numbers correspond to section of text addressing selected clinical issue. From: Treatment of Symptoms of the Menopause: An Endocrine Society Clinical Practice.
Fig. 1. Mean BMI and BMI Z-score (se) of the children with AA, TA, and TT genotypes in rs9939609 of the FTO gene. The P values are for the additive model.

Fig. 1. Mean BMI and BMI Z-score (se) of the children with AA, TA, and TT genotypes in rs of the FTO gene. The P values are for the additive model.
Fig. 1. Correlation of TSH with TC, LDL-C, HDL-C, and TG.

Fig. 1. Correlation of TSH with TC, LDL-C, HDL-C, and TG.
Figure 2 Top panel shows mean (SE) differences in near-final height (cm) (n = 71) in the AI, GH, and AI/GH groups regardless of length of treatment (n.

Figure 2 Top panel shows mean (SE) differences in near-final height (cm) (n = 71) in the AI, GH, and AI/GH groups regardless of length of treatment (n.
Fig. 1. Study enrollment and disposition of participants

Fig. 1. Study enrollment and disposition of participants
Figure 1. Illustrative 24-h serum LH concentration (IRMA) profiles and calculated LH secretory rates as determined by deconvolution analysis in one healthy.

Figure 1. Illustrative 24-h serum LH concentration (IRMA) profiles and calculated LH secretory rates as determined by deconvolution analysis in one healthy.
Fig. 2. Plasma melatonin secretion profiles for each of the eight subjects across the three conditions in the study. Profiles are shown for the entire.

Fig. 2. Plasma melatonin secretion profiles for each of the eight subjects across the three conditions in the study. Profiles are shown for the entire.
Figure 1. Variable region amino acid sequences of TPO-reactive Fab heavy chains. The putative most homologous germline sequence is shown in full, with.

Figure 1. Variable region amino acid sequences of TPO-reactive Fab heavy chains. The putative most homologous germline sequence is shown in full, with.

Similar presentations

Ads by Google