1. Recent Advancements of Bortezomib in Acute Lymphocytic Leukemia Treatment
Acta Haematol 2013;129:207– DOI: /
Fig. 1. The intracellular pathways and proteins affected by proteasome inhibition with bortezomib. Ros = Reactive oxygen species; JNK = c-Jun N-terminal kinase.
© 2013 S. Karger AG, Basel

2. Recent Advancements of Bortezomib in Acute Lymphocytic Leukemia Treatment
Acta Haematol 2013;129:207– DOI: /
Fig. 2. Bortezomib treatment led to inhibition of BCR-ABL-induced suppression of FoxO proteins and their proapoptotic targets in Ph + ALL patients.
© 2013 S. Karger AG, Basel