1. Contribution of nitric oxide synthase (NOS) in blood–brain barrier disruption during acute focal cerebral ischemia in normal rat 
Mohammad T. Mohammadi, S. Mostafa Shid-Moosavi, Gholam A. Dehghani 
Pathophysiology 
Volume 19, Issue 1, Pages (February 2012)
DOI: /j.pathophys
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2. Fig. 1
The average mean arterial blood pressure (MAP) in Sham, Control, l-Arginine and l-NAME groups of rats. All values are mean±SEM. *Significantly different from l-Arginine group only during reperfusion (p<0.05).
Pathophysiology  , 13-20DOI: ( /j.pathophys )
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3. Fig. 2
Regional cerebral blood flow (rCBF; % from baseline) before and during MCAO, and the first 15-min reperfusion period in Sham, Control, l-Arginine and l-NAME groups of rats. All values are mean±SEM. *Significantly different from Sham group (p<0.05).
Pathophysiology  , 13-20DOI: ( /j.pathophys )
Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions

4. Fig. 3
Neurological deficit score (NDS) after 12h reperfusion in Control, l-Arginine and l-NAME groups of rats. All values are mean±SEM. *Significantly different from Control and l-Arginine groups (p<0.05).
Pathophysiology  , 13-20DOI: ( /j.pathophys )
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5. Fig. 4
Effects of l-Arginine and l-NAME on the cerebral infarct volume (mm3). All values are mean±SEM. *Significantly different from Control and l-Arginine groups (p<0.05).
Pathophysiology  , 13-20DOI: ( /j.pathophys )
Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions

6. Fig. 5
Brain water content (BWC) of right and left hemispheres of Sham and ischemic rats of Control, l-Arginine and l-NAME groups. All values are mean±SEM. *Significantly different from Sham and their own left hemispheres (p<0.05). +Significantly different from ipsilateral hemispheres of Control and l-Arginine groups (p<0.05).
Pathophysiology  , 13-20DOI: ( /j.pathophys )
Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions

7. Fig. 6
Edema formation (%) and tissue swelling of lesioned hemispheres (%) in Control, l-Arginine and l-NAME groups. All values are mean±SEM. *Significantly different from Control and l-Arginine groups (p<0.05).
Pathophysiology  , 13-20DOI: ( /j.pathophys )
Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions

8. Fig. 7
Photograph of rats’ brain that received an IV infusion of EB. In A (Sham group) the BBB was intact and the EB extravasation was absent. The bluish colors of the right hemispheres of ischemic rats show the occurrence of BBB disruption in B (Control), C (l-Arginine) and D (l-NAME groups). (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)
Pathophysiology  , 13-20DOI: ( /j.pathophys )
Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions

9. Fig. 8
EB concentrations (μg/g) in the brain tissues of the left and the right hemispheres of Sham, Control, l-Arginine and l-NAME groups. All values are mean±SEM. *Significantly different from Sham and their own left hemispheres (p<0.05) +Significantly different from ipsilateral hemisphere of Control and l-Arginine groups (p<0.05).
Pathophysiology  , 13-20DOI: ( /j.pathophys )
Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions