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Progressing subglottic and tracheobronchial stenosis in a patient with CHARGE syndrome diagnosed in adulthood  Keiko Mitaka Komatsuzaki, Shinichi Shimomura,

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Presentation on theme: "Progressing subglottic and tracheobronchial stenosis in a patient with CHARGE syndrome diagnosed in adulthood  Keiko Mitaka Komatsuzaki, Shinichi Shimomura,"— Presentation transcript:

1 Progressing subglottic and tracheobronchial stenosis in a patient with CHARGE syndrome diagnosed in adulthood  Keiko Mitaka Komatsuzaki, Shinichi Shimomura, Yutaka Tomishima, Takayuki Honda, Kazuhiro Fukasawa, Toshio Oyama, Yoshihiro Miyashita  Respiratory Medicine Case Reports  Volume 12, Pages (January 2014) DOI: /j.rmcr Copyright © 2014 The Authors Terms and Conditions

2 Fig. 1 Bronchoscopy revealed pin-hall-like stenosis with fibrous tissue in the subglottic area. Vocal cord (arrow head). Respiratory Medicine Case Reports  , 24-26DOI: ( /j.rmcr ) Copyright © 2014 The Authors Terms and Conditions

3 Fig. 2 Initial computed tomography (CT) scan (a) and CT scan 6 years following tracheostomy (b). The entire circumference of the trachea progressed to severe stenosis. Respiratory Medicine Case Reports  , 24-26DOI: ( /j.rmcr ) Copyright © 2014 The Authors Terms and Conditions

4 Fig. 3 The autopsy (hematoxylin and eosin stain, magnification) (a) ×1, (b) ×100, and (c) ×200. Structure of the main bronchus seen severe stenosis with squamous metaplasia, non-specific elevated granulomatous formation, and hyperplasia of the bronchial glands. Respiratory Medicine Case Reports  , 24-26DOI: ( /j.rmcr ) Copyright © 2014 The Authors Terms and Conditions


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