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Reduced complement activation and improved postoperative performance after cardiopulmonary bypass with heparin-coated circuits  Piet G.M. Jansen, MD,

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Presentation on theme: "Reduced complement activation and improved postoperative performance after cardiopulmonary bypass with heparin-coated circuits  Piet G.M. Jansen, MD,"— Presentation transcript:

1 Reduced complement activation and improved postoperative performance after cardiopulmonary bypass with heparin-coated circuits  Piet G.M. Jansen, MD, PhDa, Henk te Velthuis, PhDa, Rien A.J.M. Huybregts, MDa, Reginald Paulus, CPa, Eisso R. Bulder, MDb, Hans I. van der Spoel, MDc, P.Dick Bezemer, PhDd, Ed H. Slaats, PhDe, León Eijsman, MD, PhDa, Charles R.H. Wildevuur, MD, PhDa  The Journal of Thoracic and Cardiovascular Surgery  Volume 110, Issue 3, Pages (September 1995) DOI: /S (95) Copyright © 1995 Mosby, Inc. Terms and Conditions

2 Fig. 1 Concentrations of fluid-phase TCC in patients treated with uncoated circuits (dotted line) or heparin-coated circuits (solid line). Data presented as medians with interquartile range. X-release, crossclamp release; *p < 0.05 between groups; ×p < compared with baseline values; + p < 0.05 compared with baseline values. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (95) ) Copyright © 1995 Mosby, Inc. Terms and Conditions

3 Fig. 2 Concentrations of PMN elastase in patients treated with uncoated circuits (dotted line) or heparin-coated circuits (solid line). Data presented as medians with interquartile range. There were no differences between groups at distinct sample moments. X-release, Crossclamp release; ×p < compared with baseline values; + p < 0.05 compared with baseline values. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (95) ) Copyright © 1995 Mosby, Inc. Terms and Conditions

4 Fig. 3 Scatter diagram of pooled data of post-CPB peak levels of fluid-phase TCC and post-CPB peak levels of PMN elastase. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (95) ) Copyright © 1995 Mosby, Inc. Terms and Conditions

5 Fig. 4 Difference between rectal temperature and peripheral skin temperature (ΔDT) measured during first 18 hours after operation in patients treated with uncoated circuits (dottedline) or heparin-coated circuits (solid line). Data presented as means plus or minus standard error of mean. *p< 0.05 between groups. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (95) ) Copyright © 1995 Mosby, Inc. Terms and Conditions

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