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Volume 64, Issue 3, Pages (September 2013)

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Presentation on theme: "Volume 64, Issue 3, Pages (September 2013)"— Presentation transcript:

1 Volume 64, Issue 3, Pages 421-430 (September 2013)
Immediate Post–Transurethral Resection of Bladder Tumor Intravesical Chemotherapy Prevents Non–Muscle-invasive Bladder Cancer Recurrences: An Updated Meta- analysis on 2548 Patients and Quality-of-Evidence Review  Nathan Perlis, Alexandre R. Zlotta, Joseph Beyene, Antonio Finelli, Neil E. Fleshner, Girish S. Kulkarni  European Urology  Volume 64, Issue 3, Pages (September 2013) DOI: /j.eururo Copyright © 2013 European Association of Urology Terms and Conditions

2 Fig. 1 Flow diagram outlining search results and final included and excluded studies. BCa=bladder cancer; MIBC=muscle-invasive bladder cancer; IVC=intravesical chemotherapy; RCT=randomized controlled trial; RFI=recurrence-free interval. European Urology  , DOI: ( /j.eururo ) Copyright © 2013 European Association of Urology Terms and Conditions

3 Fig. 2 Risk-of-bias graph: reviews of authors’ judgments about each risk-of-bias item presented as percentages across all included studies. European Urology  , DOI: ( /j.eururo ) Copyright © 2013 European Association of Urology Terms and Conditions

4 Fig. 3 Forest plot comparing recurrence-free interval in patients receiving intravesical chemotherapy versus controls. CI=confidence interval; IV=inverse variance; SE=standard error. European Urology  , DOI: ( /j.eururo ) Copyright © 2013 European Association of Urology Terms and Conditions

5 Fig. 4 Funnel plot examining the possibility of publication bias. The plot was created by comparing the variance with effect size in publications comparing recurrence-free interval of patients receiving intravesical chemotherapy versus controls. SE=standard error. European Urology  , DOI: ( /j.eururo ) Copyright © 2013 European Association of Urology Terms and Conditions

6 Fig. 5 Forest plot comparing early recurrences (within 1 yr) between patients receiving immediate intravesical chemotherapy after transurethral resection of bladder tumor versus controls. CI=confidence interval; IV=inverse variance; SE=standard error. European Urology  , DOI: ( /j.eururo ) Copyright © 2013 European Association of Urology Terms and Conditions

7 Fig. 6 Forest plot comparing bladder cancer progression (to muscle invasion) between patients receiving intravesical chemotherapy after transurethral resection of bladder tumor versus controls. CI=confidence interval; IV=inverse variance; SE=standard error. European Urology  , DOI: ( /j.eururo ) Copyright © 2013 European Association of Urology Terms and Conditions


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