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High-Resolution Computed Tomographic Features of Bronchiolitis Obliterans Organizing Pneumonia
Koichi Nishimura, M.D., Harumi Itoh, M.D. CHEST Volume 102, Issue 1, Pages (July 1992) DOI: /chest.102.1_Supplement.26S Copyright © 1992 The American College of Chest Physicians Terms and Conditions
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FIGURE 1 (upper). Posteroanterior chest roentgenogram from a 57-year-old man with BOOP shows air-space consolidation in the left upper zone. (Lower) Roentgenogram after 1 month from the same patient shows air-space consolidation in the right upper zone and linear opacities in the left middle zone. Without corticosteroid treatment, the area of consolidation migrated to the contralateral lung. CHEST , 26-31DOI: ( /chest.102.1_Supplement.26S) Copyright © 1992 The American College of Chest Physicians Terms and Conditions
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FIGURE 2 Posteroanterior chest roentgenogram of a 57-year-old man with BOOP shows diffuse reticular and linear infiltrates. This image illustrates the difficulty in distinguishing BOOP from UIP. CHEST , 26-31DOI: ( /chest.102.1_Supplement.26S) Copyright © 1992 The American College of Chest Physicians Terms and Conditions
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FIGURE 3 High-resolution CT of a 57-year-old man with BOOK Two main CT findings are observable. One is a marked increase in lung density (marked as 1) and the other is a slight increase in lung density (marked as 2). CHEST , 26-31DOI: ( /chest.102.1_Supplement.26S) Copyright © 1992 The American College of Chest Physicians Terms and Conditions
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FIGURE 4 High-resolution CT through the right upper lung shows areas with marked increases in lung density exhibiting a nodular appearance. Note areas of about 1 cm in diameter that correspond to the size of secondary pulmonary lobules. CHEST , 26-31DOI: ( /chest.102.1_Supplement.26S) Copyright © 1992 The American College of Chest Physicians Terms and Conditions
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FIGURE 5 Summary of HRCT findings in 9 patients with BOOK
CHEST , 26-31DOI: ( /chest.102.1_Supplement.26S) Copyright © 1992 The American College of Chest Physicians Terms and Conditions
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FIGURE 6 Schematic of the panlobular distribution. The left figure is derived from serial sections of inflated and fixed normal lungs and the right figure indicates the panlobular distribution. Each secondary pulmonary lobule is marked differently in the left figure. In polygonal sharply marginated areas of increased attenuation of about 1 cm in diameter, the panlobular distribution is estimated as illustrated on the right. CHEST , 26-31DOI: ( /chest.102.1_Supplement.26S) Copyright © 1992 The American College of Chest Physicians Terms and Conditions
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FIGURE 7 Stereomicrophotograph of an inflated biopsy specimen. Terminal air spaces are filled with materials that correspond to airspace consolidation observed on HRCT images. CHEST , 26-31DOI: ( /chest.102.1_Supplement.26S) Copyright © 1992 The American College of Chest Physicians Terms and Conditions
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FIGURE 8 Photomicrograph of a biopsy specimen of BOOP under low magnification (hematoxylin-eosin stain). Note that the boundary between the 2 areas exhibiting different histologic findings is formed by the interlobular septum or the pulmonary vein. CHEST , 26-31DOI: ( /chest.102.1_Supplement.26S) Copyright © 1992 The American College of Chest Physicians Terms and Conditions
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