1. From: Short Pulse of Clinical Concentration of Bevacizumab Modulates Human Retinal Pigment Epithelial Functionality
Invest. Ophthalmol. Vis. Sci ;57(3): doi: /iovs
Figure Legend:
Effect of short incubation with BEV on cell apoptosis. Gene-specific expression pattern of apoptotic genes (bax, bcl2, caspase 9) was evaluated with qRT-PCR from PRPE cells (A) that were incubated with BEV (2 hours) or left untreated. Active caspase staining was performed by FLICA active caspase staining kit. Active caspase staining (green) was analyzed with an immunofluorescence microscope on PRPE cells in the presence and absence of BEV (representative images) (B–G). The results of the qRT-PCR were normalized with gapdh levels. Statistical analysis was performed using Student's t-test (*P < 0.05, **P < 0.01, ***P < 0.005) (n ≥ 3).
Date of download: 10/24/2017
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