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Effects of chronic treatment with valproate and oxcarbazepine on testicular development in rats  Ali Cansu, Özgür Ekinci, Ayse Serdaroglu, Seren Gulsen.

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Presentation on theme: "Effects of chronic treatment with valproate and oxcarbazepine on testicular development in rats  Ali Cansu, Özgür Ekinci, Ayse Serdaroglu, Seren Gulsen."— Presentation transcript:

1 Effects of chronic treatment with valproate and oxcarbazepine on testicular development in rats 
Ali Cansu, Özgür Ekinci, Ayse Serdaroglu, Seren Gulsen Gürgen, Özalp Ekinci, Deniz Erdogan, Zafer Kutay Coskun, Lutfi Tunc  Seizure - European Journal of Epilepsy  Volume 20, Issue 3, Pages (April 2011) DOI: /j.seizure Copyright © 2010 British Epilepsy Association Terms and Conditions

2 Fig. 1 Apoptosis in spermatogonium with TUNEL staining. Seminiferous tubules of the control (A), VPA (B) and OXC groups (C) (): TUNEL-positive spermatogonium cells at 400×, inset: () TUNEL-positive spermatogonium cells at 100× TUNEL staining. Seizure - European Journal of Epilepsy  , DOI: ( /j.seizure ) Copyright © 2010 British Epilepsy Association Terms and Conditions

3 Fig. 2 TGF-β1 immunoreactivity of the primary spermatocyte in seminiferous tubules. This is strong in the control group (A), weak in the VPA group (B) and moderate in the OXC group (C). (): 400×. Seizure - European Journal of Epilepsy  , DOI: ( /j.seizure ) Copyright © 2010 British Epilepsy Association Terms and Conditions


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