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Ductal Carcinoma In Situ With Microinvasion: Prognostic Implications, Long-Term Outcomes, and Role of Axillary Evaluation  Rahul R. Parikh, M.D., Bruce.

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Presentation on theme: "Ductal Carcinoma In Situ With Microinvasion: Prognostic Implications, Long-Term Outcomes, and Role of Axillary Evaluation  Rahul R. Parikh, M.D., Bruce."— Presentation transcript:

1 Ductal Carcinoma In Situ With Microinvasion: Prognostic Implications, Long-Term Outcomes, and Role of Axillary Evaluation  Rahul R. Parikh, M.D., Bruce G. Haffty, M.D., Donald Lannin, M.D., Meena S. Moran, M.D.  International Journal of Radiation Oncology • Biology • Physics  Volume 82, Issue 1, Pages 7-13 (January 2012) DOI: /j.ijrobp Copyright © 2012 Elsevier Inc. Terms and Conditions

2 Fig. 1 Ten-year local relapse-free survival rates by pathology. Local relapse occurred in 22 of the 321 patients (6.8%) with ductal carcinoma in situ (DCIS) and 6 of the 72 patients (8.3%) with DCIS with microinvasion (DCISM). The 10-year breast local relapse-free survival rates for the DCIS and DCISM groups were 89.0% and 90.7%, respectively (p = 0.36, log-rank test). International Journal of Radiation Oncology • Biology • Physics  , 7-13DOI: ( /j.ijrobp ) Copyright © 2012 Elsevier Inc. Terms and Conditions

3 Fig. 2 Ten-year distant metastasis-free survival rates by pathology. With a total of four distant metastases over 10 years, the ductal carcinoma in situ (DCIS) group experienced a 98.5% metastasis-free survival rate, vs. 97.9% in the DCIS with microinvasion (DCISM) group (p = 0.77, log-rank test). International Journal of Radiation Oncology • Biology • Physics  , 7-13DOI: ( /j.ijrobp ) Copyright © 2012 Elsevier Inc. Terms and Conditions

4 Fig. 3 Ten-year overall survival rates by pathology. The 10-year overall survival rates for the ductal carcinoma in situ (DCIS) and DCIS with microinvasion (DCISM) groups were 93.2% and 95.7%, respectively (p = 0.93, log-rank test). International Journal of Radiation Oncology • Biology • Physics  , 7-13DOI: ( /j.ijrobp ) Copyright © 2012 Elsevier Inc. Terms and Conditions

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