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Volume 105, Issue 2, Pages (February 1994)

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1 Volume 105, Issue 2, Pages 524-533 (February 1994)
Two Studies of the Clinical Effectiveness of the Nicotine Patch With Different Counseling Treatments  Michael C. Fiore, M.D., Susan L. Kenford, B.S., Douglas E. Jorenby, Ph.D., David W. Wetter, M.S., Stevens S. Smith, Ph.D., Timothy B. Baker, Ph.D.  CHEST  Volume 105, Issue 2, Pages (February 1994) DOI: /chest Copyright © 1994 The American College of Chest Physicians Terms and Conditions

2 Figure 1 End-of-treatment (S week) and 6-month abstinence rates (point prevalence) and time to relapse (survival functions) for study 1. Statistical results. Efficacy (point prevalence): end of treatment χ2(1) = 3.33, p < 0.05; 6-month χ2(1) = 1.89, p = Survival analysis: Wilcoxon χ2(1) = p < 0.02; log-rank χ2(1) = 4.33, p < Note that percentages are not directly comparable between the two graphs due to slightly different definitions of abstinence. CHEST  , DOI: ( /chest ) Copyright © 1994 The American College of Chest Physicians Terms and Conditions

3 Figure 2 Study 1 weekly mean withdrawal ratings for subjects receiving active and placebo patch. + Data for week 9 were collected approximately 3 days postpatch therapy. CHEST  , DOI: ( /chest ) Copyright © 1994 The American College of Chest Physicians Terms and Conditions

4 Figure 3 End-of-treatment (6 week) and 6-month abstinence rates (point prevalence) and time to relapse (surviv al functions) for study 2. Statistical results. Efficacy (point prevalence): end of treatment χ2(1) = 3.89, p < 0.05; 6-month χ2(1) = 2.70, p = Survival analysis: Wilcoxon χ2(1) = 5.76, p < 0.02, log-rank χ2(1) = 4.51, p0.05. Note that percentages are not directly comparable between the two graphs due to slightly different definitions of abstinence. CHEST  , DOI: ( /chest ) Copyright © 1994 The American College of Chest Physicians Terms and Conditions

5 Figure 4 Study 2, weekly mean withdrawal ratings for subjects receiving active and placebo patch. CHEST  , DOI: ( /chest ) Copyright © 1994 The American College of Chest Physicians Terms and Conditions


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