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In certain patients with the long QT syndrome, potassium channel function is reduced (diagonal arrows), which leads to prolongation of the action potential.

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Presentation on theme: "In certain patients with the long QT syndrome, potassium channel function is reduced (diagonal arrows), which leads to prolongation of the action potential."— Presentation transcript:

1 In certain patients with the long QT syndrome, potassium channel function is reduced (diagonal arrows), which leads to prolongation of the action potential of ventricular myocytes and prolongation of the QT interval. In some cases, reactivation of sodium and calcium channels can lead to triggered activity that can initiate life-threatening ventricular arrhythmias. Source: Cardiovascular Disorders: Heart Disease, Pathophysiology of Disease: An Introduction to Clinical Medicine, 7e Citation: Hammer GD, McPhee SJ. Pathophysiology of Disease: An Introduction to Clinical Medicine, 7e; 2013 Available at: Accessed: October 16, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved

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