1. Myelodysplastic syndrome. (Bone marrow aspirate, 100 ×
Myelodysplastic syndrome. (Bone marrow aspirate, 100 ×.) Note increased number of erythroid cells with basophilic cytoplasm. Many of these red blood cell precursors have a "tapioca pudding"-like appearance consistent with dyssynchrony between nuclear and cytoplasmic maturation in the erythroid series. These findings alone in the red blood cell line would be consistent with a megaloblastic picture. The finding of dysmorphic changes in the granulocyte maturation or megakaryocyte maturation helps establish the diagnosis of myelodysplastic syndrome. (Used, with permission, from L Damon.)
Source: Blood Disorders, Current Medical Diagnosis & Treatment 2017
Citation: Papadakis MA, McPhee SJ, Rabow MW. Current Medical Diagnosis & Treatment 2017; 2016 Available at: Accessed: October 16, 2017
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