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Usefulness of Cardiac Troponins as Markers of Early Treatment Response in Cardiac Sarcoidosis  Riina Kandolin, MD, Jukka Lehtonen, MD, Juhani Airaksinen,

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Presentation on theme: "Usefulness of Cardiac Troponins as Markers of Early Treatment Response in Cardiac Sarcoidosis  Riina Kandolin, MD, Jukka Lehtonen, MD, Juhani Airaksinen,"— Presentation transcript:

1 Usefulness of Cardiac Troponins as Markers of Early Treatment Response in Cardiac Sarcoidosis 
Riina Kandolin, MD, Jukka Lehtonen, MD, Juhani Airaksinen, MD, Tapani Vihinen, MD, Heikki Miettinen, MD, Kari Kaikkonen, MD, Petri Haataja, MD, Tuomas Kerola, MD, Markku Kupari, MD  American Journal of Cardiology  Volume 116, Issue 6, Pages (September 2015) DOI: /j.amjcard Copyright © 2015 Elsevier Inc. Terms and Conditions

2 Figure 1 The early response of plasma hs-cTnT (A) and hs-cTnI (B) to steroid therapy in all 38 CS patients who underwent the 4-week repeat measurement. The p values are from Wilcoxon signed-rank test for paired comparisons. The dashed horizontal line stands for the upper limit of the normal reference range. The y axis is logarithmic. American Journal of Cardiology  , DOI: ( /j.amjcard ) Copyright © 2015 Elsevier Inc. Terms and Conditions

3 Figure 2 All hs-cTnT (A) and hs-cTnI (B) measurements taken before initiation of steroids and at 3, 6, and 12 months of treatment. The numbers in the panel indicate the number of studied patients/number of patients under follow-up at each time point. The associated p values are from Wilcoxon signed-rank paired comparisons versus the pretreatment measurements. The dashed horizontal line indicates the upper limit of normal range. The y axis is logarithmic. American Journal of Cardiology  , DOI: ( /j.amjcard ) Copyright © 2015 Elsevier Inc. Terms and Conditions

4 Figure 3 Kaplan-Meier curves for survival free of adverse cardiac events for patients with elevated versus normal hs-cTnT/I at the start of follow-up. American Journal of Cardiology  , DOI: ( /j.amjcard ) Copyright © 2015 Elsevier Inc. Terms and Conditions


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