1. Volume 50, Issue 3, Pages 498-505 (September 2006)
High Incidence of Prostate Cancer Detected by Saturation Biopsy after Previous Negative Biopsy Series 
Jochen Walz, Markus Graefen, Felix K.-H. Chun, Andreas Erbersdobler, Alexander Haese, Thomas Steuber, Thorsten Schlomm, Hartwig Huland, Pierre I. Karakiewicz 
European Urology 
Volume 50, Issue 3, Pages (September 2006)
DOI: /j.eururo
Copyright © 2006 European Association of Urology Terms and Conditions

2. Fig. 1
Model calibration plots. (A) Calibration plot for prediction of cancer on saturation biopsy according to percent of free PSA level, where x-axis represents predicted probability of prostate cancer and y-axis represents observed fraction with evidence of prostate cancer on saturation biopsy according to percent of free PSA. Calibration plot for prediction of prostate cancer on saturation biopsy using the full (B) and reduced (C) prediction model, where x-axis represents the full (B) or reduced (C) model, respectively, and predicted probability of prostate cancer on saturation biopsy; y-axis represents observed fraction with evidence of prostate cancer on biopsy. Perfect prediction would correspond to the 45-degree line. Points estimated below the 45-degree line correspond to nomogram overprediction, whereas points situated above the 45-degree line correspond to nomogram underprediction.
European Urology  , DOI: ( /j.eururo )
Copyright © 2006 European Association of Urology Terms and Conditions

3. Fig. 2
Nomograms. To obtain nomogram predicted probability of saturation biopsy (for full and reduced model), locate the patient’s variable values at each axis. Draw a vertical line to the “Point” axis to determine how many points are attributed for each variable value. Sum the points for all variables. Locate the sum on the “Total Points” line. Draw a vertical line towards the Prob. of CA axis to determine the patient cancer probability. PSA=prostate specific antigen; %fPSA=percent free PSA; PSAD=PSA density; TZ-D=transition zone density; Tot.Vol=total prostatic volume; TZVol=transition zone volume; Prev. bx=number of previous biopsies; # cores=planned number of cores; Prob. of PCa=probability of prostate cancer.
European Urology  , DOI: ( /j.eururo )
Copyright © 2006 European Association of Urology Terms and Conditions