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Hyaluronic acid skin fillers: Adverse reactions and skin testing

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1 Hyaluronic acid skin fillers: Adverse reactions and skin testing
Nicholas J. Lowe, MD, FRCPa,b,c, C.Anne Maxwell, MB, ChBa, Philippa Lowe, MB, ChBa, Michael G. Duickb, Kishor Shah, MDa,d  Journal of the American Academy of Dermatology  Volume 45, Issue 6, Pages (December 2001) DOI: /mjd Copyright © 2001 American Academy of Dermatology, Inc Terms and Conditions

2 Fig. 1 Skin-tested forearm 8 weeks after intradermal injection of HA filler (Hylaform) with severe grade III inflammatory reaction. Journal of the American Academy of Dermatology  , DOI: ( /mjd ) Copyright © 2001 American Academy of Dermatology, Inc Terms and Conditions

3 Fig. 2 Example of delayed inflammatory reaction to HA filler (Hylaform) occurring 8 weeks after implantation. Journal of the American Academy of Dermatology  , DOI: ( /mjd ) Copyright © 2001 American Academy of Dermatology, Inc Terms and Conditions

4 Fig. 3 Another patient showing inflammatory skin reactions 7 weeks after implantation (Hylaform). Journal of the American Academy of Dermatology  , DOI: ( /mjd ) Copyright © 2001 American Academy of Dermatology, Inc Terms and Conditions

5 Fig. 4 A and B, Histologic features of biopsy specimen taken from skin affected by inflammatory reaction (see text for description of features). A deep, predominantly lymphocytic and plasma cell infiltrate is seen (Hylaform). Journal of the American Academy of Dermatology  , DOI: ( /mjd ) Copyright © 2001 American Academy of Dermatology, Inc Terms and Conditions


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