Presentation is loading. Please wait.

Presentation is loading. Please wait.

Does BCG vaccination protect against childhood asthma

Published byCynthia Beasley Modified over 6 years ago

Similar presentations

Presentation on theme: "Does BCG vaccination protect against childhood asthma"— Presentation transcript:

1 Does BCG vaccination protect against childhood asthma
Does BCG vaccination protect against childhood asthma? Final results from the Manchester Community Asthma Study retrospective cohort study and updated systematic review and meta-analysis  Mary F. Linehan, PhD, Ulugbek Nurmatov, PhD, Timothy L. Frank, MD, Robert M. Niven, MD, David N. Baxter, PhD, Aziz Sheikh, MD  Journal of Allergy and Clinical Immunology  Volume 133, Issue 3, Pages e14 (March 2014) DOI: /j.jaci Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2 Fig 1 Updated Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) flow diagram. Journal of Allergy and Clinical Immunology  , e14DOI: ( /j.jaci ) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3 Fig E1 A, Forest plot (fixed-effects model) showing ORs and 95% CIs for the association between BCG vaccination and asthma. B, Funnel plot for the association between BCG vaccination and asthma. C, Forest plot (random-effects model) showing ORs and 95% CIs for the association between BCG vaccination and asthma in category B studies. Journal of Allergy and Clinical Immunology  , e14DOI: ( /j.jaci ) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

4 Fig E2 A, Forest plot (random-effects model) showing ORs and 95% CIs for the association between BCG vaccination and sensitization measured by using specific IgE level. B, Funnel plot for the association between BCG vaccination and a positive specific IgE level. Journal of Allergy and Clinical Immunology  , e14DOI: ( /j.jaci ) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

5 Fig E3 A, Forest plot (fixed-effects model) showing ORs and 95% CIs for the association between BCG vaccination and a positive SPT response. B, Funnel plot for the association between BCG vaccination and a positive SPT response. Journal of Allergy and Clinical Immunology  , e14DOI: ( /j.jaci ) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

6 Fig E4 A, Forest plot (random-effects model) showing ORs and 95% CIs for the association between BCG and atopic dermatitis/eczema. B, Funnel plot for the association between BCG vaccination and eczema/atopic dermatitis. Journal of Allergy and Clinical Immunology  , e14DOI: ( /j.jaci ) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

7 Fig E5 A, Forest plot (random-effects model) showing ORs and 95% CIs for the association between BCG and allergic rhinoconjunctivitis. B, Funnel plot for the association between BCG vaccination and rhinoconjunctivitis. Journal of Allergy and Clinical Immunology  , e14DOI: ( /j.jaci ) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

8 Fig E6 A, Forest plot (fixed-effects model) showing ORs and 95% CIs for the association between BCG vaccination and allergy in general. B, Funnel plot for the association between BCG vaccination and allergy in general. C, Forest plot (fixed-effects model) showing ORs and 95% CIs for the association between BCG vaccination and allergy in general in category B studies. Journal of Allergy and Clinical Immunology  , e14DOI: ( /j.jaci ) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Download ppt "Does BCG vaccination protect against childhood asthma"

Similar presentations

Early exposure to cow's milk protein is protective against IgE-mediated cow's milk protein allergy Yitzhak Katz, MD, Nelly Rajuan, MSc, Michael R. Goldberg,

Early exposure to cow's milk protein is protective against IgE-mediated cow's milk protein allergy Yitzhak Katz, MD, Nelly Rajuan, MSc, Michael R. Goldberg,
Control of immunopathology during chikungunya virus infection Caroline Petitdemange, PhD, Nadia Wauquier, PhD, Vincent Vieillard, PhD Journal of Allergy.

Control of immunopathology during chikungunya virus infection Caroline Petitdemange, PhD, Nadia Wauquier, PhD, Vincent Vieillard, PhD Journal of Allergy.
Characteristics of childhood peanut allergy in the Australian Capital Territory, 1995 to 2007 Raymond James Mullins, MBBS, PhD, FRACP, FRCPA, Keith B.G.

Characteristics of childhood peanut allergy in the Australian Capital Territory, 1995 to 2007 Raymond James Mullins, MBBS, PhD, FRACP, FRCPA, Keith B.G.
Jonathan A. Bernstein, MD, David M. Lang, MD, David A. Khan, MD 

Jonathan A. Bernstein, MD, David M. Lang, MD, David A. Khan, MD 
The natural history of soy allergy

The natural history of soy allergy
Acid-suppressive medications during pregnancy and risk of asthma and allergy in children: A systematic review and meta-analysis  Rebecca E. Devine, MPH,

Acid-suppressive medications during pregnancy and risk of asthma and allergy in children: A systematic review and meta-analysis  Rebecca E. Devine, MPH,
Kyoung-Bok Min, MD, PhD, Jin-Young Min, PhD 

Kyoung-Bok Min, MD, PhD, Jin-Young Min, PhD 
Santa Jeremy Ono, BA, PhD, Mark B. Abelson, MD 

Santa Jeremy Ono, BA, PhD, Mark B. Abelson, MD 
Stephen J. Fowler, MD, Gaël Tavernier, PhD, Robert Niven, MD 

Stephen J. Fowler, MD, Gaël Tavernier, PhD, Robert Niven, MD 
Maritta S. Jaakkola, MD, PhD, Reginald Quansah, PhD, Timo T

Maritta S. Jaakkola, MD, PhD, Reginald Quansah, PhD, Timo T
Acid-suppressive medications during pregnancy and risk of asthma and allergy in children: A systematic review and meta-analysis  Rebecca E. Devine, MPH,

Acid-suppressive medications during pregnancy and risk of asthma and allergy in children: A systematic review and meta-analysis  Rebecca E. Devine, MPH,
Serum vitamin D levels and severe asthma exacerbations in the Childhood Asthma Management Program study  John M. Brehm, MD, MPH, Brooke Schuemann, BS,

Serum vitamin D levels and severe asthma exacerbations in the Childhood Asthma Management Program study  John M. Brehm, MD, MPH, Brooke Schuemann, BS,
Low vitamin D levels are associated with atopic dermatitis, but not allergic rhinitis, asthma, or IgE sensitization, in the adult Korean population  Hui.

Low vitamin D levels are associated with atopic dermatitis, but not allergic rhinitis, asthma, or IgE sensitization, in the adult Korean population  Hui.
A genome-wide association study to identify genetic determinants of atopy in subjects from the United Kingdom  Yize I. Wan, BMedSci, David P. Strachan,

A genome-wide association study to identify genetic determinants of atopy in subjects from the United Kingdom  Yize I. Wan, BMedSci, David P. Strachan,
Is 9 more than 2 also in allergic airway inflammation?

Is 9 more than 2 also in allergic airway inflammation?
Jonathan A. Bernstein, MD, David M. Lang, MD, David A. Khan, MD 

Jonathan A. Bernstein, MD, David M. Lang, MD, David A. Khan, MD 
Joe K. Gerald, MD, PhD, Roni Grad, MD, William C. Bailey, MD, Lynn B

Joe K. Gerald, MD, PhD, Roni Grad, MD, William C. Bailey, MD, Lynn B
Meta-analysis of filaggrin polymorphisms in eczema and asthma: Robust risk factors in atopic disease  Elke Rodríguez, MSc, Hansjörg Baurecht, MSc, Esther.

Meta-analysis of filaggrin polymorphisms in eczema and asthma: Robust risk factors in atopic disease  Elke Rodríguez, MSc, Hansjörg Baurecht, MSc, Esther.
An Infant with Atopic Dermatitis and Itching After Ingestion of Milk

An Infant with Atopic Dermatitis and Itching After Ingestion of Milk
Endogenous and exogenous sex steroid hormones in asthma and allergy in females: A systematic review and meta-analysis  Nicola McCleary, PhD, Bright I.

Endogenous and exogenous sex steroid hormones in asthma and allergy in females: A systematic review and meta-analysis  Nicola McCleary, PhD, Bright I.

Similar presentations

Ads by Google