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Management of independent motion between multiple targets in lung cancer radiation therapy
Feng Liu, PhD, An Tai, PhD, Ergun Ahunbay, PhD, Elizabeth Gore, MD, Candice Johnstone, MD, X. Allen Li, PhD Practical Radiation Oncology Volume 7, Issue 1, Pages (January 2017) DOI: /j.prro Copyright © 2016 American Society for Radiation Oncology Terms and Conditions
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Figure 1 A representative case of 2 targets showing the changes in the target volume and distance of center of mass in (A) transverse, (B) 3-dimensional, (C) coronal, and (D) sagittal views for the planning (in red) and on-treatment (in green) computed tomography scans aligned with the centers of masses of the large target. Practical Radiation Oncology 2017 7, 26-34DOI: ( /j.prro ) Copyright © 2016 American Society for Radiation Oncology Terms and Conditions
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Figure 2 Distributions of on-treatment deviations in distances between centers of mass (DCOMs) between 2 targets from their values in the original plans. Practical Radiation Oncology 2017 7, 26-34DOI: ( /j.prro ) Copyright © 2016 American Society for Radiation Oncology Terms and Conditions
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Figure 3 Typical dose-volume histograms of the adaptive (solid line) and repositioning (dashed line) plans for 2 on-treatment computed tomography scans of 2 patients. CTV, clinical target volume; PTV, planning target volume. Practical Radiation Oncology 2017 7, 26-34DOI: ( /j.prro ) Copyright © 2016 American Society for Radiation Oncology Terms and Conditions
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Figure 4 The averages of clinical target volume (CTV) (A) V100 and (B) minimum dose received by 99% of the CTV volume (D99) of the repositioning, adaptive, and reoptimization plans for each patient in comparison with the original plan. For patient 8, 2 sub-CTVs are not well-separated and are treated as 1. Practical Radiation Oncology 2017 7, 26-34DOI: ( /j.prro ) Copyright © 2016 American Society for Radiation Oncology Terms and Conditions
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Figure 5 Large clinical target volume (CTV) coverage receiving at least 100% of the prescribed dose (V100) for the repositioning plans as a function of volume ratios between on-treatment to the planning computed tomography (CT) scans (A) for all patients and (B) for the 3 patients with volume increases during the treatment. Practical Radiation Oncology 2017 7, 26-34DOI: ( /j.prro ) Copyright © 2016 American Society for Radiation Oncology Terms and Conditions
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