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Analysis of Macular Edema after Cataract Surgery in Patients with Diabetes Using Optical Coherence Tomography  Stephen J. Kim, MD, Robert Equi, MD, Neil.

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Presentation on theme: "Analysis of Macular Edema after Cataract Surgery in Patients with Diabetes Using Optical Coherence Tomography  Stephen J. Kim, MD, Robert Equi, MD, Neil."— Presentation transcript:

1 Analysis of Macular Edema after Cataract Surgery in Patients with Diabetes Using Optical Coherence Tomography  Stephen J. Kim, MD, Robert Equi, MD, Neil M. Bressler, MD  Ophthalmology  Volume 114, Issue 5, Pages (May 2007) DOI: /j.ophtha Copyright © 2007 American Academy of Ophthalmology Terms and Conditions

2 Figure 1 Top, Mean central point thickness and central subfield retinal thickness (micrometers) of study eyes preoperatively (pre-op) and 1 and 3 months after cataract surgery. Bottom, Representative range of cystoid abnormalities of study eyes with macular edema. Left, Preoperative optical coherence tomography (OCT). Right, One-month postoperative OCT. Ophthalmology  , DOI: ( /j.ophtha ) Copyright © 2007 American Academy of Ophthalmology Terms and Conditions

3 Figure 2 Mean change in center point thickness (micrometers) from preoperative baseline at 1 and 3 months after surgery among study eyes grouped according to risk characteristics: non–insulin dependence (NIDDM) versus insulin dependence (IDDM), duration of diabetes < or ≥ 10 years, and by history of treated clinically significant macular edema (CSME). Ophthalmology  , DOI: ( /j.ophtha ) Copyright © 2007 American Academy of Ophthalmology Terms and Conditions

4 Figure 3 Mean change in visual acuity (VA; logarithm of the minimum angle of resolution [logMAR]) from preoperative best-corrected VA at 1 and 3 months after surgery among study participants grouped according to risk characteristics: non–insulin dependence (NIDDM) versus insulin dependence (IDDM), duration of diabetes < or ≥ 10 years, and by history of treated clinically significant macular edema (CSME). *P = at 1 month. Ophthalmology  , DOI: ( /j.ophtha ) Copyright © 2007 American Academy of Ophthalmology Terms and Conditions

5 Figure 4 Mean change in center point thickness (micrometers) from preoperative measurements at 1 and 3 months after surgery among study participants with varying levels of diabetic retinopathy: none and mild (retinopathy that was mild and nonproliferative or less severe), all (any retinopathy, including mild, moderate, and severe nonproliferative, and proliferative), advanced (moderate nonproliferative, severe nonproliferative, proliferative). *P = 0.05 with reference to the none group at 1 and 3 months. Ophthalmology  , DOI: ( /j.ophtha ) Copyright © 2007 American Academy of Ophthalmology Terms and Conditions

6 Figure 5 Mean change in visual acuity (VA; logarithm of the minimum angle of resolution [logMAR]) from preoperative best-corrected VA at 1 and 3 months after surgery among study participants with varying levels of diabetic retinopathy: none and mild (retinopathy that was mild nonproliferative or less severe), all (any retinopathy, including mild, moderate, and severe nonproliferative, and proliferative), advanced (moderate nonproliferative, severe nonproliferative, proliferative). *P = 0.08 with reference to the none group at 1 month. Ophthalmology  , DOI: ( /j.ophtha ) Copyright © 2007 American Academy of Ophthalmology Terms and Conditions

7 Figure 6 Mean change in logarithm of the minimum angle of resolution (logMAR) visual acuity (VA) among study eyes with <30% and >30% increases in foveal thickness at 1 month (▨) and mean change in logMAR VA of the entire study group at 1 month (▩). *P<0.001, comparing mean change in logMAR VA between <30% and >30% groups. **P = 0.01, comparing mean change in logMAR VA between >30% group and study mean. Ophthalmology  , DOI: ( /j.ophtha ) Copyright © 2007 American Academy of Ophthalmology Terms and Conditions

8 Figure 7 Mean center point thicknesses (micrometers) preoperatively (pre-op) and 1 and 3 months postoperatively of 11 study eyes that developed macular edema (ME) and 39 study eyes that did not develop macular edema. *P<0.001. Ophthalmology  , DOI: ( /j.ophtha ) Copyright © 2007 American Academy of Ophthalmology Terms and Conditions

9 Figure 8 Mean change in logarithm of the minimum angle of resolution (logMAR) vision from preoperative best-corrected visual acuity at 1 and 3 months among study participants with macular edema (ME) (▨; 11 study eyes) and without ME (▩; 39 study eyes). *P> **P = 0.01. Ophthalmology  , DOI: ( /j.ophtha ) Copyright © 2007 American Academy of Ophthalmology Terms and Conditions

10 Figure 9 Mean change in center point thickness (micrometers) from preoperative baseline at 1 and 3 months of eyes with a history of resolved clinically significant macular edema treated with or without intraoperative triamcinolone acetonide. N = no. of study eyes. *P = **One study eye was lost to follow-up. Ophthalmology  , DOI: ( /j.ophtha ) Copyright © 2007 American Academy of Ophthalmology Terms and Conditions

11 Figure 10 Mean change in logarithm of the minimum angle of resolution (logMAR) visual acuity (VA) from preoperative best-corrected VA at 1 and 3 months among eyes with a history of resolved clinically significant macular edema treated with or without intraoperative steroids. N = no. of study eyes. *One study eye was lost to follow-up. Ophthalmology  , DOI: ( /j.ophtha ) Copyright © 2007 American Academy of Ophthalmology Terms and Conditions


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