1. Interleukin-6–dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly conserved enhancer by Dennis Löffler, Katja Brocke-Heidrich, Gabriele Pfeifer, Claudia Stocsits, Jörg Hackermüller, Antje K. Kretzschmar, Renate Burger, Martin Gramatzki, Conny Blumert, Kay Bauer, Helena Cvijic, A. Kerstin Ullmann, Peter F. Stadler, and Friedemann Horn Blood Volume 110(4):1330-1333 August 15, 2007 ©2007 by American Society of Hematology

2. A highly conserved enhancer is responsible for the Stat3-mediated responsiveness of the miR- 21 promoter to IL-6. Dennis Löffler et al. Blood 2007;110:1330-1333 ©2007 by American Society of Hematology

3. miR-21 is induced by IL-6 via Stat3 activation and promotes survival of myeloma cells. Dennis Löffler et al. Blood 2007;110:1330-1333 ©2007 by American Society of Hematology