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Nuclear Reprogramming in Cells by J. B. Gurdon, and D. A. Melton Science Volume 322(5909):1811-1815 December 19, 2008 Published by AAAS.

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Presentation on theme: "Nuclear Reprogramming in Cells by J. B. Gurdon, and D. A. Melton Science Volume 322(5909):1811-1815 December 19, 2008 Published by AAAS."— Presentation transcript:

1 Nuclear Reprogramming in Cells by J. B. Gurdon, and D. A. Melton Science Volume 322(5909):1811-1815 December 19, 2008 Published by AAAS

2 Fig. 1. Designs of nuclear transfer experiments (A) to unfertilized eggs (second meiotic metaphase) of frogs or mammals or (B) to first meiotic frog oocytes. J. B. Gurdon, and D. A. Melton Science 2008;322:1811-1815 Published by AAAS

3 Fig. 2. Nuclear transfer success decreases as donor cells differentiate (3, 8). J. B. Gurdon, and D. A. Melton Science 2008;322:1811-1815 Published by AAAS

4 Fig. 3. Nuclei enlarge and chromatin decondenses during nuclear reprogramming. J. B. Gurdon, and D. A. Melton Science 2008;322:1811-1815 Published by AAAS

5 Fig. 4. Chromosomal protein exchange in a normal cell (left) or after nuclear transfer to an egg or oocyte (right). J. B. Gurdon, and D. A. Melton Science 2008;322:1811-1815 Published by AAAS

6 Fig. 5. Four experimental routes for nuclear reprogramming. J. B. Gurdon, and D. A. Melton Science 2008;322:1811-1815 Published by AAAS


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