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Electrosmog Low frequency magnetic and electric fields  Electric household appliances (Razors, hairdryers, etc)  Fluorescent lighting (separates + and.

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Presentation on theme: "Electrosmog Low frequency magnetic and electric fields  Electric household appliances (Razors, hairdryers, etc)  Fluorescent lighting (separates + and."— Presentation transcript:

1 Electrosmog Low frequency magnetic and electric fields  Electric household appliances (Razors, hairdryers, etc)  Fluorescent lighting (separates + and – wiring)  Lamp or alarm-clock on nightstand (if plug the wrong way and ungrounded)  Electric wiring in home  Near-by powerline  Laptop computer  Wrist watch  Switched-off cell phone in pocket known biomedical effects:  decreases pineal function with decreased melatonin production (insomnia, lowered immune status  opens blood brain barrier  Autism and other neuro-developmental disorders in exposed infants  increased leukemia and cancer rates  brain fog, fatigue, short term memory loss  synergistic effect with all other types of radiation

2 Int J Cancer. 2001 Mar 1;91(5):728-35 –Residential magnetic fields as a risk factor for childhood acute leukaemia: results from a German population-based case-control study. –Schuz J, Grigat JP, Brinkmann K, Michaelis J.Schuz JGrigat JPBrinkmann KMichaelis J –Institute for Medical Statistics and Documentation, University of Mainz, Mainz, Germany. schuez@imsd.uni-mainz.de –Our objective was to investigate whether exposure to residential power-frequency (50 Hz) magnetic fields above 0.2 microT increases a child's risk of leukaemia and to confirm or reject a finding from a previous German study on this topic, which reported increased leukaemia risk with exposure to stronger magnetic fields during the night. A population-based case-control study was used, covering the whole of the former West Germany. Residential magnetic fields were measured over 24 hr for 514 children with acute leukaemia identified by the German Childhood Cancer Registry and 1,301 control children taken from population registration files. Magnetic fields above 0.2 microT were relatively rare in Germany (only 1.5% of the study population). Childhood leukaemia and 24 hr median magnetic fields were only weakly related (OR = 1.55, 95% CI 0.65-3.67). A significant association was seen between childhood leukaemia and magnetic field exposure during the night (OR = 3.21, 95% CI 1.33-7.80). –A dose-response-relationship was observed after combining the data of all German studies on magnetic fields and childhood leukaemia. The evidence for an association between childhood leukaemia and magnetic field exposure in our study comes from a measure of exposure during the night. Despite the large size of our study, the results are based on small numbers of exposed children. If the observed association stands, the effect on a population level in Germany would be small. Significant association found between childhood leukemia and magnetic field exposure during the night

3 Electric blankets used prenatal and postnatally associated with leukemia and brain cancer Am J Epidemiol. 1990 May;131(5):763-73 –Comment in: Am J Epidemiol. 1990 May;131(5):774-5. –Magnetic field exposure from electric appliances and childhood cancer. Savitz DA, John EM, Kleckner RC.Savitz DAJohn EMKleckner RC –Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill 27599. –The effect on childhood cancer of prolonged exposure to 60-H magnetic fields from electric appliances was examined using interview data from a recently completed case-control study. Exposures of children aged 0-14 years whose incident cancers were diagnosed between 1976 and 1983 and who resided in the Denver, Colorado, Standard Metropolitan Statistical Area were compared with those of controls selected by random digit dialing, matched on age, sex, and telephone exchange area. Parents of 252 cases and 222 controls were interviewed at home about the use of electric appliances by the mother during pregnancy (prenatal exposure) and by the child (postnatal exposure). After adjustment for income, prenatal electric blanket exposure was associated with a small increase in the incidence of childhood cancers (odds ratio (OR) = 1.3, 95% confidence interval (CI) 0.7-2.2) that was more pronounced for leukemia (OR = 1.7, 95% CI 0.8-3.6) and brain cancer (OR = 2.5, 95% CI 1.1-5.5). Postnatal exposure to electric blankets was also weakly associated with childhood cancer (OR = 1.5, 95% CI 0.6-3.4), with a larger but imprecise association with acute lymphocytic leukemia (OR = 1.9, 95% CI 0.6-6.5). Water beds and bedside electric clocks were unrelated to childhood cancer incidence. Results are limited by nonresponse and imprecision resulting from the rarity of appliance use, especially for subgroups of cases. – Nonetheless, electric blankets, one of the principal sources of prolonged magnetic field exposure, were weakly associated with childhood cancer and warrant a more thorough evaluation.

4 Int J Cancer. 1999 Jul 19;82(2):161-70 –A case-control study of childhood leukemia in southern Ontario, Canada, and exposure to magnetic fields in residences. Green LM, Miller AB, Villeneuve PJ, Agnew DA, Greenberg ML, Li J, Donnelly KE.Green LMMiller ABVilleneuve PJAgnew DAGreenberg MLLi JDonnelly KE –Department of Public Health Sciences, University of Toronto, Canada. lm.green@utoronto.ca –A population-based case-control study was conducted in Ontario, Canada, to assess the relation between the risk of childhood leukemia and residential exposure to magnetic fields. Participating subjects consisted of 201 cases, diagnosed at 0 to 14 years of age during 1985- 1993, ascertained from the records at the Hospital for Sick Children (Toronto), and 406 individually matched controls. Where possible, point-in-time measurements of magnetic fields were made in all residences occupied by subjects during the period of inquiry in the defined catchment area. Three different classification schemes of wire code were assigned to each residence. Detailed information was collected by interviewer-administered questionnaires, which enabled risk estimates to be adjusted for socio-economic characteristics, medical history of parent(s) and child and environmental exposures. Inconsistent elevations in risk were associated with time-weighted averages of magnetic fields both inside and outside the home for subjects having residential point-in-time measurements that represented at least 70% of their etiological period. These risks increased in magnitude when analysis was restricted to children under 6 years of age at diagnosis or to those with acute lymphoblastic leukemia. –For children younger than 6 years at diagnosis, outside perimeter measurements of the residence, > or = 0.15 microT, were associated with increased leukemia risk (OR = 3.45, 95% CI = 1.14-10.45). Evaluation of different exposure times for point-in-time magnetic field measurements and wire configuration suggested that exposures earliest in the etiological period were associated with greater risks for children diagnosed at a younger age (OR = 2.50, 95% CI = 1.14-5.49). Increase risk of childhood leukemia associated with magnetic fields inside and outside of the home, especially in children under 6 years of age

5 Occup Environ Med. 2002 Feb;59(2):92-7 –Risk of birth defects by parental occupational exposure to 50 Hz electromagnetic fields: a population based study. Blaasaas KG, Tynes T, Irgens A, Lie RT.Blaasaas KGTynes TIrgens ALie RT –National Institute of Occupational Health, Oslo, Norway. karl.g.blaasaas@nrpa.no –OBJECTIVES: To study the risk of birth defects by parental occupational exposure to 50 Hz electromagnetic fields. METHODS: The Medical Birth Registry of Norway was linked with census data on parental occupation. An expert panel constructed a job exposure matrix of parental occupational exposure to 50 Hz magnetic fields. Exposure to magnetic fields was estimated by combining branch and occupation into one of three exposure levels: 24 hours/week above approximately 0.1 mu T. Risks of 24 categories of birth defects were compared across exposure levels. Out of all 1.6 million births in Norway in the period 1967-95, 836,475 and 1,290,298 births had information on maternal and paternal exposure, respectively. Analyses were based on tests for trend and were adjusted for parents' educational level, place of birth, maternal age, and year of birth. RESULTS: The total risk of birth defects was not associated with parental exposure. Maternal exposure was associated with increased risks of spina bifida (p=0.04) and clubfoot (p=0.04). A negative association was found for isolated cleft palate (p=0.01). Paternal exposure was associated with increased risks of anencephaly (p=0.01) and a category of "other defects" (p=0.02). –CONCLUSION: The present study gives an indication of an association between selected disorders of the central nervous system and parental exposure to 50 Hz magnetic fields. Given the crude exposure assessment, lack of comparable studies, and the high number of outcomes considered, the results should be interpreted with caution. Parental exposure to 50Hz electromagnetic fields associated with increased risks of spina bifida, club foot, and anencephaly

6 Epidemiology. 2003 Jul;14(4):420-6; discussion 427-8 –Neurodegenerative diseases in welders and other workers exposed to high levels of magnetic fields. Hakansson N, Gustavsson P, Johansen C, Floderus B.Hakansson NGustavsson PJohansen CFloderus B –Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. niclas.hakansson@imm.ki.se –BACKGROUND: Previous work has suggested an increase in risk of amyotrophic lateral sclerosis (ALS) and Alzheimer's disease among workers exposed to extremely low- frequency magnetic fields (ELF-MF). We evaluated the relation between ELF-MF from occupational exposures and mortality from neurodegenerative diseases. METHODS: The study was based on a cohort of Swedish engineering industry workers, comprising 537,692 men and 180,529 women. The cohort was matched against the 3 most recent censuses and The Causes of Death Registry. Levels of ELF-MF exposure were obtained by linking occupation according to the censuses to a job exposure matrix. We used 4 levels of exposure and considered both the primary and contributing causes of death, 1985-96. RESULTS: The risk of Alzheimer's disease as primary or contributing cause of death increased with increasing exposure to ELF-MF among both men and women, with a relative risk (RR) of 4.0 and a 95% confidence interval (95% CI) of 1.4-11.7 in the highest exposure group for both sexes combined. There was a RR of 2.2 (95% CI: 1.0-4.7) for ALS in the highest exposure group with the suggestion of an exposure-response relationship. No evidence of increased risk was seen for Parkinson's disease or multiple sclerosis. –CONCLUSIONS: The findings support previous observations of an increased risk of Alzheimer's disease and ALS among employees occupationally exposed to ELF-MF. Further studies based on morbidity data are warranted. Increased risk of ALS and Alzheimer's disease in workers exposed to high levels of extemely low frequency magnetic fields

7 Epidemiology. 2000 Sep;11(5):539-43 –Exposure to electromagnetic fields and risk of central nervous system disease in utility workers. Johansen C.Johansen C –Institute of Cancer Epidemiology, the Danish Cancer Society, Copenhagen. –Occupational exposure to electromagnetic fields has been associated with neurological diseases such as amyotrophic lateral sclerosis, senile dementia, Parkinson disease, and Alzheimer disease. I studied the incidence of central nervous system diseases in 30,631 persons employed in Danish utility companies between 1900 and 1993. I linked the cohort to the nationwide, population-based Danish National Register of Patients and compared the numbers of cases of these diseases observed between 1978 and 1993 with the corresponding rates in the general population. In addition I fit to the data on utility workers a multiplicative Poisson regression model in relation to estimated levels of exposure to 50-Hz electromagnetic fields. Overall, there was an increase in risk for senile dementia and motor neuron diseases combined. The incidences of Parkinson disease, Alzheimer disease, and other diseases of the central nervous system were essentially unrelated to exposure to electromagnetic fields. A decreased risk of epilepsy compared with the general population probably reflects a healthy worker effect; I observed an increased risk of epilepsy based on internal comparisons. –The increased risk for senile dementia and motorneuron diseases may be associated with above-average levels of exposure to electromagnetic fields. Increased risk of senile dementia and motor neuron diseases may be associated with an above average level of electromagnetic field exposure

8 Pediatr Blood Cancer. 2006 Aug 29 –Paternal occupational exposure to electro-magnetic fields as a risk factor for cancer in children and young adults: A case-control study from the North of England. Pearce MS, Hammal DM, Dorak MT, McNally RJ, Parker L.Pearce MSHammal DMDorak MTMcNally RJParker L –Paediatric and Lifecourse Epidemiology Research Group, School of Clinical Medical Sciences (Child Health), University of Newcastle upon Tyne, UK. –BACKGROUND: Numerous studies have implied that paternal occupational exposures, in particular electromagnetic fields (EMF) and ionizing radiation, may be involved in the etiology of childhood cancers. We investigated whether an association exists between paternal occupations at birth involving such exposures and cancer risk in offspring, using data from the Northern Region Young Persons' Malignant Disease Registry (NRYPMDR). PROCEDURE: Cases (n = 4,723) were matched, on sex and year of birth, to controls from two independent sources: (i) all other patients from the NRYPMDR with a different cancer, (ii) 100 cancer-free individuals per case from the Cumbrian Births Database. An occupational exposure matrix was used to assign individuals to exposure groups. RESULTS: There was an increased risk of leukemia among the offspring of men employed in occupations likely to be associated with EMF or radiation exposures (OR 1.31, 95% CI 1.02-1.69), particularly in males aged less than 6 years (OR 1.81, 95% 1.19-2.75). No significant association was seen in females. Increased risks were also seen for chondrosarcoma (OR 8.7, 95% CI 1.55-49.4) and renal carcinoma (OR 6.75, 95% CI 1.73-26.0). These associations were consistent between control groups and remained after adjustment for socio-economic status. – CONCLUSIONS: This large case-control study identified a significantly increased risk of leukemia among the offspring of men likely to have been occupationally exposed to EMF, with differing associations between males and females. Increased risks of chondrosarcoma and renal carcinoma were also seen, although based on smaller numbers. Further detailed investigations in this area are required to understand this association. Pediatr Blood Cancer (c) 2006 Wiley-Liss, Inc. Increased risk of leukemia, chondrosarcoma, and renal carcinoma in offspring of fathers working in occupations associated with EMF exposure

9 Epidemiology. 1998 Jul;9(4):392-7 Magnetic fields and breast cancer in Swedish adults residing near high-voltage power lines –Feychting M,Feychting M –Forssen U,Forssen U –Rutqvist LE,Rutqvist LE –Ahlbom A.Ahlbom A –Institute of Environmental Medicine, Karolinska Institutet, stockholm, Sweden. –We conducted a case-control study to test the hypothesis that residential magnetic field exposures increase the incidence of breast cancer. The study was based on people who had lived within 300 m of 220- or 400-kV power lines in Sweden at any time between 1960 and 1985. We identified 699 cases of breast cancer in women and 9 cases in men. One matched control per female case and eight per male case were selected at random. Estrogen receptor information was available for a subset of female cases. We assessed magnetic field exposure through calculations of the magnetic fields generated by the power lines before diagnosis. For calculated magnetic field levels > or = 0.2 microtesla (microT) closest in times before diagnosis, we estimated the relative risk to be 1.0 [95% confidence interval (CI) = 0.7-1.5] for women and 2.1 (95% CI = 0.3-14.1) for men. Women younger than 50 years of age at diagnosis had a relative risk of 1.8 (95% CI = 0.7-4.3). For women with estrogen receptor-positive breast cancer, the relative risk was estimated at 1.6 (95% CI = 0.6-4.1), using the exposure cutoff point > or = 0.1 microT. – Among estrogen receptor-positive women younger than 50 years at diagnosis, the relative risk increased to 7.4 (95% CI = 1.0-178.1). Residential magnetic field exposure greatly increases risk of breast cancer in women under the age of 50 who have receptors sensitive to estrogen

10 Eur J Epidemiol. 1998 Sep;14(6):563-9 –Occupational exposure to magnetic fields and brain tumours in central Sweden. –Rodvall Y,Rodvall Y –Ahlbom A,Ahlbom A –Stenlund C,Stenlund C –Preston-Martin S,Preston-Martin S –Lindh T,Lindh T –Spannare B.Spannare B –Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden. –Occupations with exposure to magnetic fields were studied in a population-based case- control study of male glioma and meningioma in Central Sweden. The study included 84 cases of glioma, 20 cases of meningioma and 155 controls. Information about job titles was obtained by means of a questionnaire. Three different methods were used to classify exposure 1) 'electrical occupations', 2) assessment of magnetic fields by an electrical engineer, 3) job values based on magnetic field measurements at work sites for occupational groups. When analyses were based on 'electrical occupations' a relative risk (RR) of 1.0 (95% CI: 0.4-2.4) was seen for glioma and 1.8 (95% CI: 0.3-3.6) for meningioma. When analyses were based on measurements a relative risk of 1.9 (95% CI: 0.8-5.0) was seen for glioma and 1.6 (95% CI: 0.3-10.2) for those ever in an exposed job of an average mean value of > 0.4 microT. A larger number of individuals was classified as exposed, when exposure was based on measurements. Information was available regarding several potential confounders, but none of them seemed to be of any importance. –Our conclusion is that the results based on magnetic field measurements give some support to the hypothesis that magnetic fields exposure may play a role in the development of brain tumours. Occupational exposure to magnetic fields associated with increased risk of brain tumors

11 Saudi Med J. 2005 Mar;26(3):405-10 Biological and morphological effects on the reproductive organ of rats after exposure to electromagnetic field. Ozguner M, Koyu A, Cesur G, Ural M, Ozguner F, Gokcimen A, Delibas N.Ozguner MKoyu ACesur GUral MOzguner FGokcimen ADelibas N –Department of Histology and Embryology, Faculty of Medicine, Suleyman Demirel University, Isparta, Turkey. mozguner@hotmail.com –OBJECTIVE: The biological effect of electromagnetic field (EMF) emitted from mobile phones is a current debate and still a controversial issue. Therefore, little is known on the possible adverse effects on reproduction as mobile phone bio-effects are only a very recent concern. The aim of this experimental study was to determine the biological and morphological effects of 900 MHz radiofrequency (RF) EMF on rat testes. METHODS: The study was performed in the Physiology and Histology Research Laboratories of Suleyman Demirel University, Faculty of Medicine, Isparta, Turkey in May 2004. Twenty adult male Sprague-Dawley rats weighing 270-320 gm were randomized into 2 groups of 10 animals: Group I (control group) was not exposed to EMF and Group II (EMF group) was exposed to 30 minutes per day, 5 days a week for 4 weeks to 900 MHz EMF. Testes tissues were submitted for histologic and morphologic examination. Testicular biopsy score count and the percentage of interstitial tissue to the entire testicular tissue were registered. Serum testosterone, plasma luteinizing hormone (LH) and follicle stimulating hormone (FSH) levels were assayed biochemically. RESULTS: The weight of testes, testicular biopsy score count and the percentage of interstitial tissue to the entire testicular tissue were not significantly different in EMF group compared to the control group. – However, the diameter of the seminiferous tubules and the mean height of the germinal epithelium were significantly decreased in EMF group (p<0.05). There was a significant decrease in serum total testosterone level in EMF group (p<0.05). –Therefore, there was an insignificant decrease in plasma LH and FSH levels in EMF group compared to the control group (p>0.05). CONCLUSION: The biological and morphological effects resulting from 900 MHz RF EMF exposure lends no support to suggestions of adverse effect on spermatogenesis, and on germinal epithelium. Therefore, testicular morphologic alterations may possibly be due to hormonal changes. EMF exposure in rats leads to decreased testosterone production

12 Electrosmog Pulsed EMF with sharp pulse rise (10- 100 Hz) DECT system (and others) of cordless phones Radar from near-by airport Alarm system in homes known biomedical effects:  disturbs all known intrinsic rhythms (EEG, heart rate variability, breathing pattern, 24 hr meridian activity, bowel movements, detoxification, etc),  blocks blood-brain and gut barrier (leaky gut syndrome) in stuck-open position leading to neurological illness (Parkinson, MS and ALS, autism,etc.), food and environmental allergies  synergistic effect with other fields, increases mold growth and mycotoxin production in homes  Lowered immune status (decreased IL-10, increased IL-1, IL-6, decreased NK cell activity)

13 Electrosmog squared: Microwave (currently around 1 billion Hz)  Cell phone radiation from base station (affects blood brain barrier in 1.6 mile radius)  Wireless internet, WLAN, etc.  Blue Tooth technology  Some home alarm systems known biomedical effects:  increases cancer rate 3 fold in 10 years after cell phone radiation is brought into a community - after a 5 year incubation period  severe EEG, HRV and EKG changes  delayed and disturbed brain development in infants  decreased melatonin and hormone production (testosterone)  open blood brain barrier with increased toxicity, affects endothelial cells in gut mucosa and endothelium (dysfunctional)  responsible for illness and death of trees  Increases growth, neurotoxin production, virulence of viruses, mold, yeast, Lyme spirochetes and other microorganisms

14 Int J Radiat Biol. 2006 Feb;82(2):69-76 –Evening exposure to mobile phone radiation affects subsequent melatonin production Wood AW,Wood AW Loughran SP,Loughran SP Stough C.Stough C –Brain Sciences Institute, Swinburne University of Technology, Hawthorn, Victoria, Australia. awood@swin.edu.au –PURPOSE: To test whether exposure to the emissions from a digital mobile phone handset prior to sleep alters the secretion of melatonin. MATERIALS AND METHODS: In a double- blind cross-over design, 55 adult volunteers were both actively exposed or sham-exposed (in random order on successive Sunday nights) to mobile phone emissions for 30 min (0.25 W average power). Urine collection occurred immediately prior to retiring to bed and on rising the next morning. Melatonin output was estimated from principal metabolite concentrations (6-sulphatoxymelatonin (aMT6s) via radioimmunoassay), urine volumes and creatinine concentrations. RESULTS: Total melatonin metabolite output (concentration x urine volume) was unchanged between the two exposure conditions (active 14.1+/-1.1 microg; sham 14.6+/-1.3 microg). The pre- and post-bedtime outputs considered separately were also not significantly different, although the pre-bedtime value was less for active versus sham exposure. When melatonin metabolite output was estimated from the ratio of aMT6s to creatinine concentrations, the pre-bedtime value was significantly less (p = 0.037) for active compared to sham. Examination of individual responses is suggestive of a small group of 'responders'. CONCLUSIONS: Total nighttime melatonin output is unchanged by mobile phone handset emissions, but there could be an effect on melatonin onset time. Mobile phone radiation decreases pre-bedtime melatonin level

15 Arch Med Res. 2005 Jul-Aug;36(4):350-5 –Oxidative damage in the kidney induced by 900-MHz-emitted mobile phone: protection by melatonin. Oktem F, Ozguner F, Mollaoglu H, Koyu A, Uz E.Oktem FOzguner FMollaoglu HKoyu AUz E –Department of Pediatric Nephrology, School of Medicine, Suleyman Demirel University, Isparta, Turkey. –BACKGROUND: The mobile phones emitting 900-MHz electromagnetic radiation (EMR) may be mainly absorbed by kidneys because they are often carried in belts. Melatonin, the chief secretory product of the pineal gland, was recently found to be a potent free radical scavenger and antioxidant. The aim of this study was to examine 900-MHz mobile phone-induced oxidative stress that promotes production of reactive oxygen species (ROS) on renal tubular damage and the role of melatonin on kidney tissue against possible oxidative damage in rats. METHODS: The animals were randomly grouped as follows: 1) sham-operated control group and 2) study groups: i) 900-MHz EMR exposed (30 min/day for 10 days) group and ii) 900- MHz EMR exposed+melatonin (100 microg kg(-1) s.c. before the daily EMR exposure) treated group. Malondialdehyde (MDA), an index of lipid peroxidation), and urine N-acetyl-beta-d- glucosaminidase (NAG), a marker of renal tubular damage were used as markers of oxidative stress-induced renal impairment. Superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) activities were studied to evaluate the changes of antioxidant status. RESULTS: In the EMR-exposed group, while tissue MDA and urine NAG levels increased, SOD, CAT, and GSH-Px activities were reduced. Melatonin treatment reversed these effects as well. In this study, the increase in MDA levels of renal tissue and in urine NAG and also the decrease in renal SOD, CAT, GSH-Px activities demonstrated the role of oxidative mechanism induced by 900-MHz mobile phone exposure, and melatonin, via its free radical scavenging and antioxidant properties, ameliorated oxidative tissue injury in rat kidney. –CONCLUSIONS: These results show that melatonin may exhibit a protective effect on mobile phone-induced renal impairment in rats. Melatonin reverses oxidative damage in the kidney induced in rats by electromagnetic radiation emitted from cell phones

16 Int J Radiat Biol. 2002 Nov;78(11):1029-36 Melatonin metabolite excretion among cellular telephone users –Burch JB, Reif JS, Noonan CW, Ichinose T, Bachand AM, Koleber TL, Yost MG.Burch JBReif JSNoonan CWIchinose TBachand AMKoleber TLYost MG –Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523, USA. james.burch@colostate.edu –PURPOSE: The relationship between cellular telephone use and excretion of the melatonin metabolite 6-hydroxymelatonin sulfate (6-OHMS) was evaluated in two populations of male electric utility workers (Study 1, n=149; Study 2, n=77). MATERIALS AND METHODS: Participants collected urine samples and recorded cellular telephone use over 3 consecutive workdays. Personal 60-Hz magnetic field (MF) and ambient light exposures were characterized on the same days using EMDEX II meters. A repeated measures analysis was used to assess the effects of cellular telephone use, alone and combined with MF exposures, after adjustment for age, participation month and light exposure. RESULTS: No change in 6- OHMS excretion was observed among those with daily cellular telephone use >25 min in Study 1 (5 worker-days). Study 2 workers with >25 min cellular telephone use per day (13 worker-days) had lower creatinine-adjusted mean nocturnal 6-OHMS concentrations (p=0.05) and overnight 6-OHMS excretion (p=0.03) compared with those without cellular telephone use. There was also a linear trend of decreasing mean nocturnal 6- OHMS/creatinine concentrations (p=0.02) and overnight 6-OHMS excretion (p=0.08) across categories of increasing cellular telephone use. A combined effect of cellular telephone use and occupational 60-Hz MF exposure in reducing 6-OHMS excretion was also observed in Study 2. –CONCLUSIONS: Exposure-related reductions in 6-OHMS excretion were observed in Study 2, where daily cellular telephone use of >25 min was more prevalent. Prolonged use of cellular telephones may lead to reduced melatonin production, and elevated 60-Hz MF exposures may potentiate the effect. Cell phone use greater than 25 minutes per day for 13 days lead to decreased melatonin production

17 Cell phone microwave radiation decreases melatonin levels: why is this bad? 1.Melatonin induces sleep. We only heal and detoxify in deep non- rem sleep. Without melatonin no regeneration and no detoxification 2. Melatonin is the most effective and potent neuroprotective chemical in the CNS and prevents damage from mercury, lead, aluminum, chemicals, mycotoxins, viruses, cigarette smoke, bacterial and parasitic endo-and exotoxins (Lyme, clostridia, ascaris) outgasing of carpets and new car plastics, etc. Sener, G.et al: “Melatonin protects against mercury induced oxidative tissue damage”. Basic and Clinical Pharmacology&Toxicology Vol 93, Dec 2003, pp 290-296

18 Mol Cell Biochem. 2006 Jan;282(1-2):83-8 –Protective effects of melatonin and caffeic acid phenethyl ester against retinal oxidative stress in long-term use of mobile phone: a comparative study. Ozguner F, Bardak Y, Comlekci S.Ozguner FBardak YComlekci S Department of Physiology, School of Medicine, Suleyman Demirel University, P. K. 13, 32100 Isparta, Turkey. drmfehmi@yahoo.com There are numerous reports on the effects of electromagnetic radiation (EMR) in various cellular systems. Melatonin and caffeic acid phenethyl ester (CAPE), a component of honeybee propolis, were recently found to be potent free radical scavengers and antioxidants. Mechanisms of adverse effects of EMR indicate that reactive oxygen species may play a role in the biological effects of this radiation. The present study was carried out to compare the efficacy of the protective effects of melatonin and CAPE against retinal oxidative stress due to long-term exposure to 900 MHz EMR emitting mobile phones. Melatonin and CAPE were administered daily for 60 days to the rats prior to their EMR exposure during our study. Nitric oxide (NO, an oxidant product) levels and malondialdehyde (MDA, an index of lipid peroxidation), were used as markers of retinal oxidative stress in rats following to use of EMR. Superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) activities were studied to evaluate the changes of antioxidant status in retinal tissue. Retinal levels of NO and MDA increased in EMR exposed rats while both melatonin and CAPE caused a significant reduction in the levels of NO and MDA. Likewise, retinal SOD, GSH-Px and CAT activities decreased in EMR exposed animals while melatonin and CAPE caused a significant increase in the activities of these antioxidant enzymes. Treatment of EMR exposed rats with melatonin or CAPE increased the activities of SOD, GSH-Px and CAT to higher levels than those of control rats. In conclusion, melatonin and CAPE reduce retinal oxidative stress after long-term exposure to 900 MHz emitting mobile phone. Nevertheless, there was no statistically significant difference between the efficacies of these two antioxidants against to EMR induced oxidative stress in rat retina. The difference was in only GSH-Px activity in rat retina. Melatonin stimulated the retinal GSH-Px activity more efficiently than CAPE did. Melatonin and caffeic acid phenyl ester reduce retinal oxidative stress after long-term expsure to 900 MHZ emitting cell phone

19 Toxicol Lett. 2005 Jul 4;157(3):257-62. Epub 2005 Apr 11 –Effects of 900 MHz electromagnetic field on TSH and thyroid hormones in rats Koyu A,Koyu A Cesur G,Cesur G Ozguner F,Ozguner F Akdogan M,Akdogan M Mollaoglu H,Mollaoglu H Ozen S.Ozen S –Department of Physiology, Suleyman Demirel University, School of Medicine, 32260 Isparta, Turkey. ahmetkoyu@tnn.net –In this study, the effects of exposure to a 900 megahertz (MHz) electromagnetic field (EMF) on serum thyroid stimulating hormone (TSH) and triiodothronine-thyroxin (T3-T4) hormones levels of adult male Sprague-Dawley rats were studied. Thirty rats were used in three independent groups, 10 of which were control (without stress and EMF), 10 of which were exposed to 900 MHz EMF and 10 of which were sham-exposed. The exposures were performed 30 min/day, for 5 days/week for 4 weeks to 900 MHz EMF. Sham-exposed animals were kept under the same environmental conditions as the study groups except with no EMF exposure. The concentration of TSH and T3-T4 hormones in the rat serum was measured by using an immunoradiometric assay (IRMA) method for TSH and a radio- immunoassay (RIA) method for T3 and T4 hormones. TSH values and T3-T4 at the 900 MHz EMF group were significantly lower than the sham-exposed group (p 0.05). –These results indicate that 900 MHz EMF emitted by cellular telephones decrease serum TSH and T3-T4 levels. Mobile phone radiation decreases TSH, T3, T4 in rats

20 Electrosmog

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24 Salford 2003: Ratbrain, 50 days post 2-hour exposure to cellphone

25 Electrosmog and Geopathic stress: poor sleeping location

26 after correction: bed moved to much better location

27 Disturbed sleeping location

28 Good sleeping location

29 Other studies and issues Schliephake, 1932 Deutsche Medizinische Wochenschrift: fatigue, restless sleep, tendency to depressive affect or abnormal excitation, headache and facial pain, drawing discomfort in scalp – especially frontal Naila, Oberfranken, Germany: retrospective study organized and paid for by local GPs: new cases of cancer increase 3 fold over 5 years after a 5 year incubation period (from year 5 to year 10 after instillation) in a radius of 400 meters around the cell phone base station (emitter) www.electrosmognews.de Similar results were found in Russian toxicological public health studies (Prof.Dr.med Hecht et al) and in Vienna (Todes-Schneise)www.electrosmognews.de Purpose of guidelines and EPA limits: to limit the accountability of the industry. The EPA limits are not the results of careful review of controlled studies Austria Medical Board 2006: stop the further development of cell phone broadcasting immediately, review current studies and finance new studies, dismantle current installations Dr.Repacholi, WHO, until recently in charge of “department for health and mobile phone industry”: remove the diagnosis “electrosensitivity” from current diagnostic codes. Convince damaged patients that they suffer from psychosomatic illness. Treat consequences of electrosmog exposure with psychotropic drugs and behavioral therapy

30 Electrosmog  Mobile phone radiation decreases pre-bedtime melatonin level Int J Radiat Biol. 2006 Feb;82(2):69-76  Serum melatonin in rats decreased by electric field exposure Bioelectromagnetics. 1994;15(5):427-37  Melatonin prevents DNA damage in rats induced by 60 Hz magnetic fields J Pineal Res. 1997 Apr; 22(3):152-62  Sener, G.et al: “Melatonin protects against mercury induced oxidative tissue damage”. Basic and Clinical Pharmacology&Toxicology Vol 93, Dec 2003, pp 290-296  Melatonin reverses oxidative damage in the kidney induced in rats by electromagnetic radiation emitted from cell phones Arch Med Res. 2005 Jul-Aug;36(4):350-5  Significant association found between childhood leukemia and magnetic field exposure during the night Int J Cancer. 2001 Mar 1;91(5):728-35

31 Electrosmog  EMF exposure in rats leads to decreased testosterone production Saudi Med J. 2005 Mar;26(3):405-10  Mobile phone radiation decreases TSH, T3, T4 in rats Toxicol Lett. 2005 Jul 4;157(3):257-262  Increased risk of senile dementia and motor neuron diseases (ALS) may be associated with an above average level of electromagnetic field exposure Epidemiology. 2000 Sep;11(5):539-43  Residential magnetic field exposure greatly increases risk of breast cancer in women under the age of 50 who have receptors sensitive to estrogen Epidemiology. 1998 Jul;9(4):392-7  Non-thermal activation of the hsp27/p38MAPK stress pathway by mobile phone radiation in human endothelial cells: molecular mechanism for cancer- and blood-brain barrier-related effects. Differentiation. 2002 May;70(2-3):120-129

32 Electrosmog Biochem J. 2007 Apr 25 Mechanism of a short-term ERK activation by electromagnetic fields at mobile phone frequency Friedman J, Kraus S, Hauptman Y, Schiff Y, Seger R.Friedman JKraus SHauptman YSchiff YSeger R The exposure to non-thermal microwave electromagnetic field generated by mobile phones affects the expression of many proteins This effect on transcription and protein stability can be mediated by the mitogen-activated protein kinase (MAPK) cascades, which serve as central signaling pathways, and govern essentially all stimulated cellular processes. Indeed, a long-term exposure of cells to mobile phone irradiation results in the activation of p38MAPKs as well as the ERK/MAPKs. Here we studied the immediate effect of irradiation on the MAPK cascades, and found that ERKs, but not stress related MAPKs are rapidly activated in response to various frequencies and intensities. Using signaling inhibitors we delineated the mechanism that is involved in this activation. We found that the first step is mediated in the plasma membrane by NADH oxidase, which rapidly generates reactive oxygen species (ROS). These ROS then directly stimulate matrix metalloproteinases and allow them to cleave and release heparin binding-EGF. This secreted factor, activates EGF receptor, which in turn further activates the ERK cascade. Thus, this study demonstrates for the first time a detailed molecular mechanism by which electromagnetic irradiation by mobile phones induces the activation of the ERK cascade and thereby induces transcription and other cellular processes.

33 Electrosmog Diagnosis Appropriate electronic instruments (very objective, but cannot predict the biological effect on the particular individual) 2. Radiaesthesia (very subjective, only 2-8 of hundred practitioners accurate) 3. ART (autonomic response testing) (very reliable in the hands of well trained practitioners) 4. Heart Rate Variability (measures accurately the biological effect of the field in this particular location on this particular organism)

34 Electrosmog Therapy Your system is by the factor of hundreds of times more sensitive during sleep. Most suggestions are based on this simple fact shut off all fuses at night. Buy a flashlight. Better: have a “demand switch” installed by knowledgeable electrician (rare to find). Move children’s bed away from wall (3 feet) Get rid of cordless phones at home and get chorded phone (Radio Shack) Use PC rather then laptop whenever possible. Have “box” as far away from chair as possible (best: outside, since computers outgas Beryllium, mercury, lead and PBDEs No wireless internet at home or in office Use metallized grounding sheet under regular bed sheet with ground wire either in earth (best) or attached to metal-waterpipe (not the ground in electric outlet, since most often 60Hz flicker on it) BiopureUS@aol.com In most cases: install metallized mosquito net (shield) to deflect incoming microwave. In office, or if possible at home: use metallized paint or conductive Silica-paint on walls Have experienced ART practitioner or Building-Biology expert check home for geopathic radiation and move bed location or work-site accordingly If you are chronically unwell or have a diagnosed medical illness and you have not responded to treatment, assume that electrosmog is keeping you from getting well. Fix it!

35 Meter to measure intensity of cell phone microwave in the home

36 Regularly give the body a stable source of pulsed microcurrent and micro-magnetic fields

37 Create a Faraday cage, especially for the children

38 Electrosmog Therapy If you do not absolutely have to use a cell phone, get rid of it. Making monthly payments drives the industry and leads to the instillation of more broadcasting panels in your neighborhood If you continue using a cell phone, get ear piece with air conduction Absolutely metal free mattress and bed-frame Un-clutter the bedroom Use melatonin at bedtime (best: sublingual) No wrist watch, no metal jewelry, no metal zippers or belt buckles Avoid living in apartments (neighbor above, below or next door may have wireless or cordless phone) or working in office buildings 10 minute earth-hole meditation at end of workday Avoid new cars (phthalates, EMF pollution) Metal free dentistry Work a life-long metal detox program Avoid electrical appliances (hair dryer, electric razor, computer) Spend less time on computer. Get a life! Follow all these recommendations and teach them to your children, parents and friends


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