1. Francesca Bisello Dosepix Midterm Review Preparatory Meeting ARDENT Project June 13th, CERN

2. Francesca Bisello, ESR 10 Midterm ARDENT Meeting, June 13 th 2013, CERN Hello everybody! Outline Dosepix Training & Conferences To do About Me.....where I come from Where I am now…

3. Francesca Bisello, ESR 10 Midterm ARDENT Meeting, June 13 th 2013, CERN About Me....in between: University of Padua: Bachelor Degree Erasmus at Ludwig Maximilians Universität München University of Bologna : Master Degree in Applied Physics Master Thesis: „Characterization of a radiochromic film Gafchromic EBT2 in relation to a Ir-192 source“, Sant´Orsola-Malpighi hospital, Bologna Hello everybody! Outline Dosepix - General To do and what I have done

4. Francesca Bisello, ESR 10 Midterm ARDENT Meeting, June 13 th 2013, CERN Overview ARDENT ESR 10 Goal Development of a medical Quality Assurance for different Xray modalities devices with Dosepix detector Methods: Chip evaluation at different radiation energy Reconstruction and analysis of Radiation Spectra Optimization of the device in different design Hello everybody! Outline Dosepix - General To do and what I have done

5. Dosepix Few words about Dosepix … Francesca Bisello, ESR 10 Midterm ARDENT Meeting, June 13 th 2013, CERN Hello everybody! Outline Dosepix - General To do and what I have done

6. Dosepix Hybrid Silicon Pixel Detector Dosepix – Hybrid Silicon Pixel Detector Read out Electronics Time- Over- Threshold Francesca Bisello, ESR 10 Midterm ARDENT Meeting, June 13 th 2013, CERN Hello everybody! Outline Dosepix - General To do and what I have done

7. Dosepix – Hybrid Silicon Pixel Detector PARAMETERSPECIFICATION Pixel Pitch220 µm x 220 µm No. of Rows16 No of Columns16 Sensitive Area3.52 mm x 3.52 mm Sensor Thickness300 µm Sensor MaterialSilicon Francesca Bisello, ESR 10 Midterm ARDENT Meeting, June 13 th 2013, CERN Hello everybody! Outline Dosepix - General To do and what I have done

8. Dosepix Hybrid Silicon Pixel Detector Dosepix – Read-out Electronics Read-out Electronics Time- Over- Threshold Francesca Bisello, ESR 10 Midterm ARDENT Meeting, June 13 th 2013, CERN Hello everybody! Outline Dosepix - General To do and what I have done

9. Dosepix – Read-out Electronics Three Operation Mode: Integration-Mode: Measure the sum of energies of incoming radiation Counting-Mode: Counts the number of events during the irradiation Dosi-Mode: Counts the number of photon in each Energy Bin Francesca Bisello, ESR 10 Midterm ARDENT Meeting, June 13 th 2013, CERN Hello everybody! Outline Dosepix - General To do and what I have done

10. Dosepix Hybrid Silicon Pixel Detector Read-out Electronics Time-Over- Threshold Dosepix – Time-Over-Threshold Francesca Bisello, ESR 10 Midterm ARDENT Meeting, June 13 th 2013, CERN Hello everybody! Outline Dosepix - General To do and what I have done

11. Dosepix – Calibration Before the measurements: Calibration Methods Francesca Bisello, ESR 10 Midterm ARDENT Meeting, June 13 th 2013, CERN Hello everybody! Outline Dosepix - Calibration To do and what I have done

12. Dosepix – Calibration ThS-EqualizationAnalogue Test PulseEnergy Binning Francesca Bisello, ESR 10 Midterm ARDENT Meeting, June 13 th 2013, CERN Hello everybody! Outline Dosepix - Calibration To do and what I have done

13. Dosepix – Threshold Equalization Different threshold pixelwise Homogeneity of the detector Detection of the noise-level Starting Point Francesca Bisello, ESR 10 Midterm ARDENT Meeting, June 13 th 2013, CERN Hello everybody! Outline Dosepix - Calibration To do and what I have done

14. Dosepix – Threshold Equalization Different threshold pixelwise Homogeneity of the detector Detection of the noise-level Goal Francesca Bisello, ESR 10 Midterm ARDENT Meeting, June 13 th 2013, CERN Hello everybody! Outline Dosepix - Calibration To do and what I have done

15. Dosepix – Threshold Equalization Different threshold pixelwise Homogeneity of the detector Detection of the noise-level Method Francesca Bisello, ESR 10 Midterm ARDENT Meeting, June 13 th 2013, CERN Hello everybody! Outline Dosepix - Calibration To do and what I have done

16. Dosepix – Analogue TestPulse Calibration 0000000000000000 0000000000000000 0000000000000000 0000000000000000 0000000000000000 0000000000000000 0000000000000000 0000000000000000 0000000000000000 0000000000000000 0000000000000000 0000000000000000 0000000000000000 0000000000000000 0000000000000000 0000000000000000 0000000000000000 0000000010000000 0000000000000001 0000000060000001 00000000120000000 00000000200100000 20000000710700003 400000001100500003 4100000013301800003 211001100249032000011 46600100072091002010 17925039220255055012536 201260510060199030417104 362607945021101140020617 97830145215310457205071097530 1302230166441711501282223062243249131 852170179551761471235376807321711445 1108801211796162238641193601902121916 92460234248267211523013825302167678178 175173013925015711412832171187021284187 147540 6553492282168014301955865126 1961880235223243230181012253015514422294 33308166806910114397902502527535 228460116107165147217199122135010614034129 8918901359918316517414115513209111983118 1261030501123289199109621810150155117156 631500146285515233114111199046194314 8721402819181254146117198950128114224146 42801999325016950040104296899 296010414920882185177302327111019 0110802080745052001151520143 030259301711601470064010150 01029114128990115002616119 000501710120011400230193 000100119702800500251 00000101270300100176 000407122023003005 0000010248060020019 0000000128000000084 000000051000000077 000000027000000046 000000019000000016 000000025000000055 00000009000000046 00000008000000024 0000000200000001 0000000100000000 0000000000000005 0000000000000000 0000000000000000 0000000000000000 0000000000000000 0000000000000000 0000000000000001 0000000000000000 0000000000000000 0000000000000000 0000000000000000 0000000000000000 0000000000000000 0000000000000000 0000000000000000 0000000400000000 0000000000000000 0000000000000000 00000001300001000 00000001000000000 00000002800006000 000000060000018000 00000004600007000 0000000136010073000 0000000146000078000 00000002310000207030 000000055000071040 0000000210070060290 000000011602000280370 0000000108056001390610 000000090053001310110 00000001190280017201400 000000068070052030 000000025401400012031990 0000000170010100131790 02000001110750023711790 0600000530750014842500 024000001940990030122210 0370000023702010062981760 057000001450440030233590 0840000099085001343780 01630000082010800942250 01170000037000021991390 02060001017069000158460 05000030190218001219440 0 000100 017700083150 0790007011010400025550 01690001215404200013510 02330001572005200015410 012000208200700017600 0126000210800500016700 09000474100600011200 01460022126000000010400 0900082471640000001500 0600011236110000001300 016003887174000000000 010009310159000000200 013007214485000000004 04006867195000000000 030016422551000000009 00001951662200000000014 000714653770000000022 000571941970000000011 000154655560000000036 00013852011840000000040 0004379112150000000054 0001011068830000000081 000201380490000000077 00024819203700000000244 0001731410700000000203 000236740300000000207 300142810000000000 000271430100000000109 210031200000000000129 410023950000000000249 1400017120000000000223 250001951000000000021 255001440000000000025 18500420000000000026 1710013200000000000208 35004800000000000149 2000570000002000031 6200120000004000085 1770070000008000041 220001800000060000178 11400400000079000085 72000000000190000021 2320000000101820000141 14500000000057000099 6900000006053000068 The pixels are „equalized“: they detect the noise at the same level of threshold Pixels Level of the Analogue Threshold Francesca Bisello, ESR 10 Midterm ARDENT Meeting, June 13 th 2013, CERN Hello everybody! Outline Dosepix - Calibration To do and what I have done

17. Dosepix – Analogue TestPulse Calibration Analogue Test Pulse Calibration Curve: Analogue Test Pulse - ToT Francesca Bisello, ESR 10 Midterm ARDENT Meeting, June 13 th 2013, CERN Hello everybody! Outline Dosepix - Calibration To do and what I have done

18. Dosepix – Energy Binning Energy Binning Francesca Bisello, ESR 10 Midterm ARDENT Meeting, June 13 th 2013, CERN Hello everybody! Outline Dosepix - Calibration To do and what I have done

19. Dosepix – Energy Calibration Energy Calibration Francesca Bisello, ESR 10 Midterm ARDENT Meeting, June 13 th 2013, CERN Energy Calibration: -Flouresce line of different material -Different for each pixel Hello everybody! Outline Dosepix - Calibration To do and what I have done

20. Dosepix - Measurements and then…measurements Francesca Bisello, ESR 10 Midterm ARDENT Meeting, June 13 th 2013, CERN Hello everybody! Outline Dosepix - Measurements To do and what I have done

21. Dosepix – Measurements I – Mammo Device IBA Dosimetry, Schwarzenbruck Energy22-35 KeV AnodeMo FiltersMo Rh DosepixDifferent experimental Setup Francesca Bisello, ESR 10 Midterm ARDENT Meeting, June 13 th 2013, CERN Hello everybody! Outline Dosepix - Measurements To do and what I have done

22. Dosepix – Measurements Energy Current 40-120 KeV 1-40 mA AnodeW Filters3,8 mm Al DosepixSlot 1: 15mm PMMA Slot 2 : Free Slot 3: 200µm Sn II – Xray Tube ECAP Erlangen University Francesca Bisello, ESR 10 Midterm ARDENT Meeting, June 13 th 2013, CERN Hello everybody! Outline Dosepix - Measurements To do and what I have done

23. Informations about Tube Energy Dosepix – Measurements Francesca Bisello, ESR 10 Midterm ARDENT Meeting, June 13 th 2013, CERN Hello everybody! Outline Dosepix - Measurements To do and what I have done

24. Define the region of use of the device : Pileup Problem Current Francesca Bisello, ESR 10 Midterm ARDENT Meeting, June 13 th 2013, CERN Hello everybody! Outline Dosepix - Measurements To do and what I have done Dosepix – Measurements

25. Informations about Pile-up Current Dosepix – Measurements Francesca Bisello, ESR 10 Midterm ARDENT Meeting, June 13 th 2013, CERN Hello everybody! Outline Dosepix - Measurements To do and what I have done

26. Hello everybody! Outline Dosepix To do and what I have done To do and what I have done: I – Fluorescence Calibration II – Pileup Understanding : Analysis of spectra with different filters MonteCarlo Simulation Monte-Carlo with EGSnrc (M.Birkner) 13 May 2013 III – Radiation Hardness Test V National School INFN Padova, 15-19 April 2013 IV – Firmware Improvement : Modify the speed of read-out New Setup V – Participation to 2013 IEEE Nuclear Science Symposium and Medical Imaging Conference, Seoul October 27- November 2 @ IBA Dosimetry: Training on Absolute and Relative Dosimetry (A. Giuliacci) End… Francesca Bisello, ESR 10 Midterm ARDENT Meeting, June 13 th 2013, CERN

27. …Thanks!