1. Nuclear Medicine in Gastrointestinal System

2. Contents GI Motility Studies GI Bleeding Scintigraphy
Pertechnetate Imaging
Salivary Gland Imaging
Hepatobiliary Imaging
Urea Breath Testing

3. GI Motility Studies
Radionuclide Esophagram
Gastroesophageal Reflux
Gastric Emptying

4. 胃食道反流显像

5. Gastroesophageal Reflux Imaging
Sensitivity is 90%
The sensitivity of X ray and endoscope is only about 40%

6. GI Bleeding Scintigraphy

7. GI Bleeding Scintigraphy
can detect bleeding rates as low as ml/min.
Sensitivity is 90%，specificity is 95%.
Incorrect localizations can be seen in 3 to 60% of cases. It is probably prudent not to base surgery solely on the results of RBC scanning.

8. Pertechnetate Imaging
Meckel's Diverticulum
Barrett's Esophagus

9. Colloid Liver Imaging
Particles between 0.3 and 1.0 microns are predominantly phagocytized by the Kupffer cells of the liver and fixed intracellularly for an indefinite period of time.

10. 肝 胶 体 显 像
显像剂

11. Colloid Liver Imaging Imaging method Patient preparation: No
Injected dose： 74~185MBq（2~5mCi）
Imaging time： after 15 min
Acquisition method：static or tomography

12. ANT
POST
LLA
RLA
Colloid Liver Imaging
Normal Image

13. Colloid Liver Imaging
POST
ANT
LLA
RLA

14. Cold area in colloid liver imaging
metastatic tumor
cyst
hepatocellular carcinoma
hematoma
hemangioma
abscess
pseudoplasm

15. Liver Blood Pool Imaging
Radiopharmaceutical
99mTc-RBC

16. Method Patient preparation: none Injected dose： 555~740MBq（15~20mCi）
Imaging time：immediately after injection and 30min, 2h.
Acquisition: dynamic, static or tomographic.

17. 肝胶体显像
肝血池显像

19. 肝动脉血供增强

20. 部分疾病肝胶体显像与肝血池显像表现

21. Hepatobiliary Imaging

22. 肝胆动态显像 二.显像剂 99mTc-HIDA 140 8.10 X10-6 2.70 X10-6 20
药物名称 γ射线能量 吸收剂量（Gy） 尿中排泄率（%）
（KeV） 肝脏 全身 （3h）
99mTc-HIDA X X
99mTc-EHIDA X X10-6 5
99mTc-DISIDA X X
99mTc-PAPADA X X
99mTc-BIDA X X10-6 2
99mTc-Mebrofenin
99mTc-PG X X
99mTc-PI X X
99mTc-PMT X X10-6 2

23. Normal Hepatobiliary Imaging
5 min
10 min
15 min
20 min
25 min
30 min
35 min
40 min
45 min

24. Normal Pattern Hepatobiliary Imaging

25. Clinical Applications
Diagnosis of acute cholecystitis.
Differentiation of obstruction outside liver and siltation of bile inside liver.
Differentiation of congenital bile tract obstruction and neonate hepatitis.
Diagnosis of common bile duct cyst.
Follow-up of therapeutic effect of liver and bile system.
Differentiation diagnosis of liver cancer, adenoma and FNHEctopic gallbladder .

26. 急 性 胆 囊 炎

27. 梗阻性黄疸
5min
10min
20min
30min
45min
60min
90min
120min
24hour

28. 完全性梗阻
1 hour
24 hour

29. Delayed Hepatobiliary Imaging
HCC (+)
5 mins
2 hours
RLA
5 hours

30. 肝肿瘤阳性显像
肝胶体显像
67Ga显像

32. Urea Breath Testing
The test is useful for initial diagnosis of H. pylori but more commonly used to document eradication or failure of initial therapy.