1. Date of download: 7/2/2016 From: Recovery Rate and Prognosis in Older Persons Who Develop Acute Lung Injury and the Acute Respiratory Distress Syndrome Ann Intern Med. 2002;136(1):25-36. doi:10.7326/0003-4819-136-1-200201010-00004 Histogram of 28-day survival by decade of age.PDepicted is the decrease in survival seen in patients with acute lung injury by decade of age (Spearman rho = 0.25; < 0.001 for comparison across all groups). The number of patients enrolled in each age group is listed above the bars; the bars represent the percentage of survivors at 28 days for each age group. Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

2. Date of download: 7/2/2016 From: Recovery Rate and Prognosis in Older Persons Who Develop Acute Lung Injury and the Acute Respiratory Distress Syndrome Ann Intern Med. 2002;136(1):25-36. doi:10.7326/0003-4819-136-1-200201010-00004 Histogram of patient outcomes—time on ventilator and death.white barsgray barsfar leftPcenterfar rightThis plot compares the percentage of patients younger than 70 years of age ( ) with the percentage of patients at least 70 years of age ( ) who were alive on the ventilator, alive off the ventilator, or dead at weekly intervals. At each time point, the percentages of younger and older patients who were alive and receiving mechanical ventilation ( ) were nearly identical ( = 1.0), but the older patients were less often alive off the ventilator ( ) and more often dead ( ). Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

3. Date of download: 7/2/2016 From: Recovery Rate and Prognosis in Older Persons Who Develop Acute Lung Injury and the Acute Respiratory Distress Syndrome Ann Intern Med. 2002;136(1):25-36. doi:10.7326/0003-4819-136-1-200201010-00004 Histogram of maximum recovery landmark achieved by 28 days among survivors.ngray barswhite barsPThe percentage of patients ( = 631) who achieved the recovery landmarks (as defined in Methods section) was similar between the group 70 years of age or older ( ) and the group younger than 70 years of age ( ) ( > 0.2). ICU = intensive care unit; SBT = spontaneous breathing trial. Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

4. Date of download: 7/2/2016 From: Recovery Rate and Prognosis in Older Persons Who Develop Acute Lung Injury and the Acute Respiratory Distress Syndrome Ann Intern Med. 2002;136(1):25-36. doi:10.7326/0003-4819-136-1-200201010-00004 Histogram of the rate of progress through recovery landmarks achieved by 28 days among survivors.Pwhite barsgray barsSBTPICUPnonsurvivorsPThe mean time from enrollment to passing a 2-hour spontaneous breathing trial was similar between both age groups ( > 0.2) ( = younger patients; = older patients). However, the older patients took more time to progress from passing the 2-hour spontaneous breathing trial ( ) to achieving 48 hours of unassisted breathing ( = 0.002) and from 48-hour unassisted breathing to being discharged from the intensive care unit ( ) without use of a ventilator ( = 0.005). Among, the patients 70 years of age or older did not differ from those younger than 70 years of age for any of these time intervals (data not shown; for all time intervals, > 0.2). Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians