1. Living Donor Kidney Transplantation Lisa Burnapp Renal Transplant Services Meeting, March 2016

2. Living Donor Transplantation Activity Actual NumbersPer million population (pmp) 2015/16 targets: 102 per month 19.0 pmp 16.7 pmpMonthly Average: 90 102 76701091007898911127888 Apr-15May-15Jun-15Jul-15Aug-15Sep-15Oct-15Nov-15Dec-15Jan-16

3. RTSM, 2016 Key Priorities – address shortfall Commissioning- Transplant Tariff development in England National Living Donor Kidney Sharing Schemes Barriers to LDKT: survey to transplant and referring centres Healthcare professional education programme (UK MET) Public engagement initiative

4. National Living Donor Kidney Sharing Schemes Performance Figures Total May 2007- Oct 2015 Pairs Registered1446 Patients Registered1314 Altruistic Donors in Paired Donation Matching Runs 119 Transplants525 NLDKSS RecordsIn a Matching Run Pairs Included261 (Jul 2015) Patients Included229 (Oct 2015 ) Altruistic Donors Included 15 (Oct 2013) Transplants Identified72 (Oct 2015) Transplants Proceeded 57 (Oct 2015) Note: each reason may account for multiple transplants

5. RTSM, 2016 Non-Directed Altruistic Donors Short Chains Long Chains December 2015 463 Donations 544 Transplants 12% of activity

6. Transplants in Highly Sensitised Patients – By Donor Source 228 217 287289 341 321 KPD = kidney paired donation RTSM, 2016

7. NLDKSS- Summary 80% (range 70-93%) of identified transplants converted to actual transplants 68% (from 39%) of transplants proceeding within dedicated shared weeks of surgery for each quarterly matching run Quarterly activity increased from Q1 (255) to Q3 (278) 29% fall in non-directed altruistic donors but 28% (from 16%) ‘opt in’ to an altruistic donor chain

8. RTSM, 2016 Commissioning Challenge Shared responsibility to deliver LDKT 2020 NHSBT is accountable for the target Commissioners responsible for funding NHSBT has partial investment in LDKT

9. RTSM, 2016 Priorities for 2016/17 Collaborate with NHS E to implement Transplant Tariff Roll out UK MET NLDKSS –Sustain improvements –Electronic offering and allocation –Increase uptake of altruistic donor chains –Modelling ABOi LDKT for highly sensitised HLAi pairs Public, patient and family engagement Donor reported outcome measures; EU Registry

10. Thank you Colleagues in transplant centres and referring units LDKT 2020 Strategy Implementation Group NHSBT –Statistical studies and audit –Information services –LKD Schemes co-ordinators –Commissioning team University of Glasgow –Dr David Manlove, Dr Gregg O’Malley RTSM, 2016